Disease conditions assoc. with neoplasms 0422

Question 1

down syndrome

Answer 1

ALL, AML

Question 2

xeroderma pigmentosum

albinism

Answer 2

skin cancer: SQUAMOUS CELL*, basal cell, melanoma

Question 3

chronic atrophic gastritis
pernicious anemia
post-surg gastric remnants

Answer 3

gastric adenocarcinoma

Question 4

tuberous sclerosis (facial angiofibroma, seizures, MR)

Answer 4

astrocytoma
angiomyolipoma
cardiac rhabdomyoma

Question 5

actinic keratosis

Answer 5

squamous cell carcinoma of skin

Question 6

barrett’s esophagus (chronic GI reflux)

Answer 6

esophageal ADENOCARCINOMA

Question 7

plummer-vinson syndrome (atrophic glossitis, esophageal webs, anemia - all due to Fe deficiency)

Answer 7

esophageal SCC

Question 8

cirrhosis: alcoholic, hep B, hep C

Answer 8

HCC

Question 9

ulcerative colitis

Answer 9

colonic adenocarcinoma

Question 10

paget’s disease of bone

Answer 10

secondary osteosarcoma and fibrosarcoma

Question 11

immunodeficiency state

Answer 11

malignant lymphoma

Question 12

AIDS

Answer 12

aggressive malignant lymphomas (non-Hodgkin) and Kaposi sarcoma

Question 13

autoimmune disease: Hashimoto thyroiditis, myasthenia gravis, etc

Answer 13

lymphoma

Question 14

acanthosis nigricans (hyperpigmentation and epidermal thickening)

Answer 14

visceral malignancy: stomach, lung, uterus

Question 15

dysplastic nevus

Answer 15

malignant melanoma

Question 16

radiation exposure

Answer 16

sarcoma
papillary thyroid cancer
leukemia
breast cancer