Disease antibody associations Flashcards
1
Q
Polymyositis/scleroderma overlap
A
PM/SCL antibody
5-10%
2
Q
Necrotising myopathy
A
Anti SRP (signal recognition protein) Confers poor prognosis
3
Q
Dermatomyositis
A
Anti Mi-2
Anti Jo-1
4
Q
Ask for myositis associated antibodies and get…
A
Anti Jo-1 (most common- 20% of PM/DM)
Anti-Mi-2
Anti-SRP
PM/SCL
5
Q
What are the sensitivity and specificity of the american college of rheumatology criteria in diagnosing RA in early disease?
A
Sens 40-60%
spec 80-90%