Direct Thrombin Inhibitors Flashcards
1
Q
Example
A
Dabigatran
2
Q
MoA
A
Thrombin
Inhibitor
Prevents thrombin from catalysing fibrin formation
Inhibits coagulation cascade
3
Q
Indications
A
Prevents DVT/PE
4
Q
ADR
A
Nausea
Haemorrhage
Hepatobiliary disorder
5
Q
Prescribing Advice
A
Amiodarone (Reduce DAPI)
Verapamil (Reduce DAPI)