Direct Thrombin Inhibitors Flashcards

1
Q

Example

A

Dabigatran

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2
Q

MoA

A

Thrombin
Inhibitor
Prevents thrombin from catalysing fibrin formation
Inhibits coagulation cascade

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3
Q

Indications

A

Prevents DVT/PE

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4
Q

ADR

A

Nausea
Haemorrhage
Hepatobiliary disorder

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5
Q

Prescribing Advice

A

Amiodarone (Reduce DAPI)

Verapamil (Reduce DAPI)

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