Diltiazem

Question 1

Diltiazem; Class

Answer 1

Calcium channel blocker

Question 2

Diltiazem; Mechanism of action

Answer 2

block influx of calcium ions into cardiac muscle.
Prevents Coronary artery spasms
Arterial and Venous Vasodilator
Reduces preload / afterload and Myocardial O2 demands

Question 3

Diltiazem; Indications

Answer 3

Control of rapid ventricular rates due to A-Flutter, A-Fib and PSVT.
Angina Pectoris

Question 4

Diltiazem; Dosage and administration

Answer 4

Adult:
0.25mg/kg initial IV push over 2 min. 
May re-bolus in 15 min if inadequate response @
0.35mg/kg re-bolus IV push over 2 min.
(Average dose of 20 mg)
Maintenance infusion: 5-15 mg/hr 
NOT RECOMMENDED FOR PEDIATRIC PT'S