Digestive System Flashcards

1
Q

How does food get into the body?

A

by absorption

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2
Q

What is the digestive system?

A

“tube” leading from one end to another

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3
Q

What are the three parts of the tonsils?

A
  1. pharyngeal
  2. palatine
  3. lingual
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4
Q

What is unique about the hyoid bone?

A

it is not connected to any other bone

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5
Q

What is the function of the epiglottis?

A

it closes the trachea when swollowing

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6
Q

What is the function if the uvula?

A

it closes off the nasopharynx when swallowing

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7
Q

What are the three types of salivary glands?

A
  1. parotid
  2. sublingual
  3. submandibular
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8
Q

What does the parotid gland secrete and what’s its function?

A

the amylase enzyme

function: helps w/ digestion

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9
Q

What does the sublingual gland secrete and what’s its function?

A

mucin

function: make saliva slimy and slick

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10
Q

What does the submandibular gland secrete?

A

both amylase and mucin

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11
Q

the cardiac sphincter is known as a ______ sphincter.

A

functional

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12
Q

What is the function of the cardiac sphincter?

A

to keep stomach contents in the stomach

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13
Q

The pyloric sphincter is know as a ______ sphincter.

A

real

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14
Q

What is the function of the pyloric sphincter?

A

to control stomach emptying

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15
Q

Chyne is a term used when…

A

food has been digested by digestive enzymes

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16
Q

What is the rugae?

A

large longitudinal folds in mucous membrane

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17
Q

The ruage allows for..

A

expansion of the stomach as needed

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18
Q

What are the 3 functions of the small intestines?

A
  1. a major digestive organ
  2. where digestion is completed
  3. almost all absorption occurs here
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19
Q

What are the three divisions of the small intestines?

A
  1. duodenum
  2. jejunum
  3. ileum
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20
Q

villi

A

increases surface area for digestion

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21
Q

villi in the small intestine have

A

microvilli for even more secretion and absorption

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22
Q

The 2 functions of large intestines are?

A
  1. absorb most of remaining H2O from indigestible food residues
  2. eliminate indigestible good residues
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23
Q

The 5 subdivision of the large intestine are?

A
  1. cecum
  2. appendix
  3. colon
  4. rectum
  5. anal canal
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24
Q

What is the function of the ileocecal valve?

A

allows digested material to pass from small intestines to large intestines

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25
Q

the ascending colon is made of what two structures?

A
  1. cecum

2. vermiform appendix

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26
Q

The internal anal sphincter is controlled by the _____ which means it is under _____ control.

A

ANS

involuntary

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27
Q

The external anal sphincter is controlled by the _____ which means it is under _____ control.

A

pudenal nerve

voluntary control

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28
Q

deglutition is AKA

A

swallowing

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29
Q

Swallowing happens in two steps, what are they?

A
  1. info. about the food is sent to the medulla of the brain which signals for swallowing
  2. tongue pushes the food back then the involuntary reflex begins
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30
Q

The three small intestine movements are…

A
  1. segmentation
  2. peristalsis
  3. opening of ileo-cecal valve
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31
Q

What type of movement begins segmentation?

A

myogenic movement

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32
Q

What type of movement begins peristalsis?

A

neurogenic movement

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33
Q

How does the ileo-cecal valve open?

A

with a hormone called gastrin

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34
Q

The three main nutrients are…

A
  1. carbohydrates
  2. proteins
  3. lipids
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35
Q

carbohydrates are made of

A

carbohydrates, disaccharides, polysaccharides

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36
Q

The main monosaccharides are

A

glucose, fructose, and galactose

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37
Q

the main disaccharides are

A

lactose, sucrose, and maltose

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38
Q

the polysaccharides include

A

starch and glycogen

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39
Q

The GI tract ONLY absorbs what type of carbohydrates…

A

simple sugars like monosaccharides

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40
Q

what makes a protein?

A

amino acids, peptides, and polypeptides

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41
Q

The GI tract ONLY absorbs what type of proteins?

A

amino acids

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42
Q

a triglyceride is made of

A
  • 3 fatty acid tails

- a glycerol backbone

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43
Q

The GI tract mainly absorbs lipids in what manner?

A
  • 2 free fatty acids

- a monoglyceride

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44
Q

What are the two types of digestion?

A
  1. physical

2. enzymatic

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45
Q

physical digestion includes…

A

mastication, milling, and segmentation

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46
Q

physical digestion increases…

A

surface area for enzymatic digestion

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47
Q

enzymatic digestion is VERY

A

pH sensitive

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48
Q

describe the mouth ‘s

  • physical digestion
  • pH
A

physical digestion: mastication

pH: 6-7 slightly acidic

49
Q

There is no digestion of _____ and _____ in the mouth.

A
  • lipids

- proteins

50
Q

what is digested enzymatically in the mouth?

A

carbs

51
Q

what enzyme digests carbs in the mouth?

A

amylase

52
Q

what type of carbs are digested through enzymes in the mouth?

A

starch

53
Q

the amylase comes from…

A

parotid salivary gland and some from the submandibular

54
Q

describe the stomach ‘s

  • physical digestion
  • pH
A

physical digestion: churning and milling

pH: 1.0-3.5

55
Q

There is no significant digestion of _____ and _____ in the stomach.

A
  • carbohydrates

- lipids

56
Q

during enzymatic digestion in the stomach chief cells and parietal cells secrete

A

pepsinogen -chief cells

HCl -parietal cells

57
Q

HCl converts pepsinogen into

A

pepsin

58
Q

what is pepsin?

A

an active digestive enzyme

59
Q

pepsin digests proteins down to

A

polypeptides

60
Q

parietal cells secrete

A

intrinsic factor

61
Q

intrinsic factor is required for

A

absorption of vitamin B12

62
Q

vitamin B12 is required for

A

erythrocyte production

63
Q

loss of intrinsic factor results in…

A

pernicious anemia

64
Q

What are the 4 types of secretion blockers for HCL?

A
  1. histamine type 2
  2. H+ proton pump inhibitor
  3. synthetic prostaglandin
  4. antacids/buffers
65
Q

what is the first effective way to reduce stomach acidity?

A

histamine type 2 blockers

66
Q

examples of histamine type 2 blockers are

A

cimetidine and ranitidine

67
Q

the H+ pump inhibitor prevents

A

HCl from being pumped by proton pumps

68
Q

examples of H+ pump inhibitor are

A

esomeprazole

lansoprazole

69
Q

synthetic prostaglandin…

A

decreases HCl, increases mucus, increases bicarbonate

70
Q

an example of a synthetic prostaglandin is

A

misoprostol

71
Q

antacids/buffers neutralize

A

stomach acids

72
Q

examples of antacids/ buffers include..

A

salts of aluminum and magnesium, (CaCO3)

73
Q

describe the small intestine’s

  • physical digestion
  • pH
A

physical digestion: segmentation

pH: 8-8.9 (alkaline)

74
Q

how does segmentation occur?

A

food stretches’ smooth muscles which then contract

75
Q

pH in the small intestine is increased by?

A
  • pancreatic juice from pancreas
  • bile from gallbladder
  • secretion from Brunner’s gland
76
Q

where is the Brunner’s gland located?

A

in the wall of duodenum

77
Q

enzymatic digestion of the small intestine includes…

A

carbohydrates, proteins, and lipids

78
Q

when carbohydrates are digested in the small intestine the pancreas secretes…

A

amylase into duodenum

79
Q

when carbohydrates are digested in the small intestine the duodenum…

A

uses amylase to break down polysaccharides

80
Q

the polysaccharides are broken down into

A

dextrin + maltose

81
Q

in the ileum dextrin is broken down by dextranase into

A

glucose, galactose, and lactose

82
Q

maltose is broken down by maltase into…

A

2 molecules of glucose

83
Q

lactose is broken down by lactase into

A

glucose + galactose

84
Q

sucrose is broken down by sucrase into

A

glucose + fructose

85
Q

what are the ratios of monosaccharide absorption in the typical diet

A
  • glucose 80%
  • galatase 10%
  • fructose 10%
86
Q

monosaccharides are absorbed into capillaries by

A

villi

87
Q

What enzyme naturally decreases by age?

A

lactase

88
Q

when proteins are digested by the small intestine the pancreas…

A

secretes peptidase into duodenum

89
Q

when digesting proteins in the small intestine the duodenum uses peptidase to break down

A

proteins and polypeptides

90
Q

when digesting proteins in the small intestine the intestinal mucosa of the ileum secretes

A

peptidase

91
Q

absorption of digestible material is into the

A

capillaries

92
Q

when digesting lipids in the small intestine the pancreas secretes

A

lipase into the duodenum

93
Q

when digesting lipids in the small intestine the duodenum uses lipase to break down

A

triglycerides

94
Q

the liver produces

A

bile

95
Q

bile is stored in the

A

gallbladder

96
Q

what does bile do?

A

it emulsifies lipids and forms micelles

97
Q

micelles which are water soluble contain

A
  • free fatty acids
  • monoglycerides
  • fat soluble vitamins
  • cholesterol
98
Q

what is the absorption process?

A

micelles are absorbed into mucosal cells…then chylomicrons from in mucosal cells go to liver for processing

99
Q

chylomicrons contain…

A

triglycerides and cholesterol

100
Q

chylomicrons are absorbed into

A

lymph vessels

101
Q

chylomicrons transport

A

absorbed lipids from gut

102
Q

chylomicrons are the lowest

A

density of all

103
Q

lipoproteins transport

A

cholesterol to and from tissue cells in body fluids

104
Q

lipoproteins solubilize

A

hydrophobic lipids

105
Q

What percent of cholesterol is in the general tissue cells and blood?

A

tissue cells- 93%

blood- 7%

106
Q

What percent of blood cholesterol is bound to a lipoprotein

A

98%

107
Q

a increase in dietary cholesterol leads to a

A

decrease in liver synthesis of cholesterol

108
Q

a decrease in dietary cholesterol leads to a

A

increase of liver synthesis of cholesterol

109
Q

LDL receptors in liver permit liver to

A
  • monitor blood conc. of LDL

- adjust cholesterol liver produces

110
Q

an increase in dietary saturated fats can

A

increase liver synthesis of cholesterol

111
Q

How does moderate exercise affect the LDL and HDL?

A
  • decrease in LDL

- increase in HDL

112
Q

cholesterol is needed for what four things

A
  1. the myelin sheath
  2. making steroid hormones
  3. integrity of skin
  4. vitamin D
113
Q

what is the etiology of familial hypercholesterolemia?

A

a mutation of gene for receptors for LDL

114
Q

the heterozygous condition of familial hypercholesterolemia causes

A

1 good 1 mutated gene

115
Q

1 good and 1 mutated gene results in

A

2-3 times increase in cholesterol

116
Q

the homozygous condition of familial hypercholesterolemia causes

A

2 mutated genes

117
Q

the 2 mutated genes results in…

A
  • almost 0 LDL receptors

- 5+ times increase in cholesterol above normal

118
Q

a decrease in the number of LDL receptors results in

A
  • decrease utilization of cholesterol
  • increase cholesterol synthesis by liver
  • increase LDL synthesis by liver
  • increase blood LDL (cholesterol)