Digestion And Mass Transport Flashcards

1
Q

What are the two types of digestion

A

physical
Chemical

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2
Q

Explain physical digestion

A

Breakdown of food through mechanical movements in the body such as chewing to increase surface area for enzymes to work on

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3
Q

Explain chemical digestion

A

Enzyme action via hydrolysis breaks down large insoluble molecules into smaller soluble ones

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4
Q

What is the function of mouth and salivary glands in digestion

A

Teeth: physical digestion, mastication breaks up food creating large surface area for enzymes to act upon
Salivary glands: release amylase to hydrolyse starch into maltose

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5
Q

Explain the function of the oesophagus in digestion

A

Uses muscle contractions to reduce volume and increase pressure to push food to back of mouth and down the oesophagus

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6
Q

Explain the function of the stomach in digestion

A

Churns food- physical digestion
Releases peptidases for the digestion of proteins into amino acids
Produces HCl for destruction of microorganisms (mainly found in proteins so is used for meat mostly)

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7
Q

What are the 3 types of peptidases

A

Exopeptidases
Endopeptidases
Dipeptidases

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8
Q

What do exopeptidases do

A

Remove terminal amino acids (amino acids from the end of the polypeptide)

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9
Q

What do endopeptidases do

A

Hydrolyse central central peptide bonds to produce shorter polypeptides

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10
Q

What do dipeptidases do

A

Hydrolyse the peptide bond between 2 amino acids

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11
Q

explain the function of the liver in digestion

A

The liver produces bile salts which are stored in the gall bladder, these emulsify lipids increasing the surface area for lipase to act upon, bile also neutralises acid

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12
Q

explain the function of the pancreas in digestion

A

Releases ‘pancreratic juice’, a mixture of pancreatic amylase, protease, and lipase
also produces alkaline salts

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13
Q

explain the function of the small intestine (ileum) in digestion

A

monomers of digestion are observed, wall is folded to form villi, each villus is coated with epithelial cells which have microvilli structures to increase surface area
ileum contains membrane bound disaccharides these digest maltose into glucose monomers

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14
Q

explain the function of the large intestine in digestion

A

absorption of water via osmosis, contains many bacteria, faeces begins to form

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15
Q

explain the function of the rectum and anus in digestion

A

rectum is where faeces is stored
anus is involved with egestion of the faeces

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16
Q

explain the features for absorption in the ileum

A

1) Many villi which are coated with many microvilli increasing surface
2) The surface of epithelial cells have microvilli a single cell thick
3) Walls of the ileum are lines with muscle which contacts to move food inside the lumen maintaining a concentration gradient
4) each villus has good blood supply

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17
Q

explain co transport of glucose/amino acids and sodium ions

A

Na+ ions are actively transported out of epithelial cells into the blood
Creates low concentration of Na+ in epithelial cells
Na+diffuses down gradient from the lumen of ileum into the epithelial cells
Glucose and amino acids are brought in with Na+ against their concentration gradient using cotransporter protein
Gluicose and amino acids then diffuse into blood by facilitated diffusion

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18
Q

explain the process of lipid absorption

A

lipid droplets are emulsified by bile salts.
Lipases digest the triglyceride into 2 fatty acids and a monoglyceride which associate with bile salts forming micelles.
At the lining of the villi micelles dissasociate and release these products as they are non polar and lipid soluble and can diffuse across the membrane.
the monoglycerides and fatty acids are transported to ER to me recombined.
the triglycerides move to golgi where they are associated with cholesterol and lipoproteins to form chylomicrons
chylomicrons are exocytosed from cell

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19
Q

Explain the structure of haemoglobin

A

Has a quaternary structure of 4 polypeptide chains (2 alpha 2 beta), each chain has a haem group containing a ferrous ion (Fe2+)

20
Q

Explain how many atoms and molecules of oxygen a haemoglobin molecule can carry

A

Each haem group can bind to an 02 molecule
4 molecules
8 atoms

21
Q

Organisms living in a low oxygen area have haemoglobin with low or high affinity

A

Low affinity so oxygen is readily released to respiring tissues

22
Q

What is a low affinity for oxygen

A

Haemoglobin that doesn’t bind to oxygen as readily

23
Q

Oxygen combining with haemoglobin results in

A

Oxyhaemoglobin

24
Q

What is the role of haemoglobin

A

Associate with oxygen at gas exchange surfaces
Dissociate oxygen readily to respiring tissues

25
How come haemoglobin perform its role
Can change its affinity for oxygen in certain conditions
26
How is oxygen loaded transported and unloaded in the blood
1. haemoglobin carries oxygen/ has high affinity for oxygen 2. loading/ uptake in the lungs 3. at high partial pressure of oxygen 4. unloads/ dissociates/ releases oxygen at respiring cells/tissues 5. at low partial pressures of oxygen 6. unloading linked to higher CO2 concentration at respiring tissues
27
How does a high partial pressure increase affinity for oxygen
Increases affinity
28
What happens to haemoglobin after an oxygen binds
Changes the tertiary structure and opens up another region for oxygen to bind (positive cooperativity)
29
How does carbon dioxide effect haemoglobins affinity
CO2 is released from respiring tissues and dissolves in the blood which produces carbonic acid. This lowers pH which changes the tertiary structure of haemoglobin. This decreases oxygen affinity and oxygen is released to respiring tissues
30
What does the shape of an oxygen dissociation curve show
More to the left: Haemoglobin has a higher affinity for oxygen at low partial pressures and so binds to it more readily More to the right: Haemoglobin has a lower affinity for oxygen at higher partial pressures and so dissociates more readily
31
What is the Bohr effect
a decrease in the amount of oxygen associated with hemoglobin and other respiratory compounds in response to a higher partial pressure of co2 and so the curve shifts to the right
32
How does car
33
How is haemoglobin adapted to small animals
Small animals have a larger surface area to volume ratio and so they lose heat more easily they therefore have a higher metabolic rate to produce more heat to counter act the loss. They therefore require a higher oxygen concentration and so haemoglobin is adapted to have a lower affinity for oxygen at any given partial pressure allowing dissociation to occur more readily
34
How is fetal haemoglobin adapted
The foetus gets oxygen form the mother through the placenta. Feral haemoglobin is adapted to have a higher affinity for oxygen than the mother and this allows the fetal haemoglobin to bind to oxygen at lower oxygen partial pressures
35
Higher partial pressure means ______ affinity
High
36
Where does haemoglobin bind
The lungs
37
what are circulatory systems needed for
-Supply substances over a large distance -Larger animals -Metabolically active organisms
38
what are the specialised features of transport systems
-Suitable meduim (most are water based as it is a solvent) -Mechanism of medium transport -Closed tubular systems (so reaches all cells) -Mass transport (moving medium in bulk)
39
how do animals control these systems
muscular contractions and active processes
40
how do plants control these systems
passive processes such as evaporation
41
what is needed for mass flow to work
-Must be unidirectional (one direction) -Have mechanisms to control and change the mass flow to suit the needs of the organism -Have mechanisms to support mass flow of specific mediums
42
how does the human body achieve whats needed for mass flow
1) Valves control unidirectional flow of blood 2) Muscular tissue in the blood vessels allow for constriction and dilation, changing pressure and thus flow 3) Intercostal muscle in thorax contracts and relaxes to change pressure
43
what is an open circulatory system
the medium transporting the nutrients around the body is not always contained in vessles and may directly make contact with tissues (small organisms)
44
what is a closed circulatory system
the medium transporting the nutrients is contained in vessels
45
what is a single system
involves transport medium only passing through once
46
what is a double system
involves transport medium passing through the heart twice