Digestion And Absorption Flashcards

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1
Q

What are two stages of digestion

A

Physical breakdown
Chemical digestion

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2
Q

What is physical breakdown

A

Break large pieces of food into smaller pieces to increase surface area for enzyme action

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3
Q

What is chemical digestion

A

Chemical breakdown of chemical food molecules into smaller soluble molecules by enzymes all of these enzymes are hydrolases where water is supplied

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4
Q

Digestion Starch to maltose in mouth

A

Salivary amylase
Hydrolysis of glucosidic bonds
Ph 7

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5
Q

What happens to salivary amylase in stomach

A

Salivary Amylase denatures
Ph 1-2

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6
Q

maltose, sucrose or lactose to constituent monosaccharides
In duodenum and ilium

A

Membrane bound maltase, lactase or sucrase hydrolyse them into constituent monosaccharides by breaking glycosidic bonds

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7
Q

What is ilium

A

Small intestine

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8
Q

How do glucose or amino acids get absorbed into blood stream

A

Sodium potassium pump means sodium goes into bloodstream by active transport
Low conc of sodium in epithelial cells and high in ilium
Co transport of glucose and sodium into cells
Glucose goes to bloodstream by facilitated diffusion

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9
Q

Protein to polypeptide

A

Stomach
Endopeptidases hydrolysis of internal peptide bonds

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10
Q

Polypeptides to dipeptides and amino acids

A

Duodenum
Exopeptidase hydrolyse external peptide bonds

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11
Q

Dipeptides to amino acids

A

Ilium
Membrane bound peptidase hydrolysis of peptide bonds

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12
Q

What is visking tubing

A

Semi permeable tube used to imitate epithelial cells around ilium

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13
Q

Two types of mutations

A

Point mutations
Chromosome mutation

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14
Q

Three types of point mutations

A

Substitution
Deletion
Insertion

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15
Q

What are the three effects of point mutation

A

Silence
Missense
Nonsense

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16
Q

What are silent mutations

A

Those that have no effect on amino acid sequence of the polypeptide

17
Q

What are missense mutations

A

Those that do alter the amino acid sequence of the polypeptide

18
Q

What are nonsense mutations

A

Those that change normal codon to stop/termination codon so synthesis of polypeptide stops