Digestion, Absorption etc Flashcards

1
Q

What is appetite?

A

Psychological desire for foods

  • driven by environmental cues (senses)
  • triggered by association
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2
Q

Hunger and satiety

A
  • physiological function
  • not food specific
  • appetite can over power hunger
  • regulated by the brain, esp hypothalamus
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3
Q

What foods keep you full longer? Shortest?

A

Protein and bulky = longer

Carbs and semi sold or liquids = shorter

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4
Q

Anatomy of the gi system

A

mouth, pharynx, esophagus, stomach, small intestine then large

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5
Q

Where does digestion start and what happen?

A
Mechanical = chewing 
Chemical = saliva mixes with food
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6
Q

Three salivary glands secret saliva that contain

A

Amylase - break down starches
Ab and enzymes - protect teeth
bicarbonate - neutralize

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7
Q

Digestion: mouth to esophagus

A

swallowing passes the food through the pharynx
once food is swallowed, becomes a bolus
swallowing causes epligottis to close trachea

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8
Q

Digestion: esophagus to stomach

A

eso has a sphincter on each end

passes through the gastrophageal sphincter to the stomach

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9
Q

Digestion: Stomach

A
  • gastric acidic juices and turns bolus into chyme

- released through the pyloric sphincter into small intestine

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10
Q

What does the gastric juices contain

“HEMI”

A
  • hydrochloric acid
  • enzymes
  • mucous: protects stomach lining
  • intrinsic factor
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11
Q

Liver excretes what during digestion

Stored where?

A

Bile - helps emulsifies fats

Gallbladder stores bile

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12
Q

Digestion: what does the pancreas secret?

What does it do?

A

Sodium bicarbonate to help neutralize chyme

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13
Q

Digestion: lipids

What is in the stomach that degrades lipids?

A

Lingual lipase and gastric lipase

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14
Q

Digestion: lipids
What is in the small intestine that helps with digestion
(2)

A
  • bile that emulsifies fat (brings water into suspension)

- pancreatic lipase

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15
Q

What are the by-product of lipids?

A

Monoaglyceride (glyceride +1 FA) and two individual FA units

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16
Q

Digestion: protein

What is in the stomach that helps with digestion?

A
  • acid denatures proteins

- pepsin: cleaves proteins into smaller

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17
Q

Digestion: proteins

What are things that can degrade peptide?

A

Small intestine

- intestinal protease, dipeptidase, tripeptidase

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18
Q

What is peristalsis and segmentation

A

1) circular and longitudinal muscles contract to move food along
2) circular muscles contract to break up food

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19
Q

Active transport

Facil

A

active; glucose and galactose

facil; fructose

20
Q

How are lipids absorbed? (ie. chylo)

A
  • intestinal cells assemble products of digestion (choles, phospho, remade triglycerides) and transports them
  • they cluster together with proteins –> chylomicron
  • chylo are released into the lymphatic system
21
Q

The role of micelles and enterocytes in absorption

Absorption of what macronutrient?

A

Lipids

  • micelles collect lipids and bring them into enterocytes
  • enterocytes (epithelial cells of intestines) absorb products of digestion
22
Q

What products can go directly into the blood?

A

Short and medium fatty acid chains

23
Q

Intestinal cells and absorb what proteins

A

Tripeptides
Dipeptides
Amoino acids

24
Q

How are tri and di broken down?

A

Broken down by tripeptidase and dipeptidase

they are broken down into the smallest unit

25
Where do broken down peptides go after absorption?
Amino acids go to the liver
26
What is competitive inhibition?
Overconsumption of one amino acids can inhibit the absorption of another
27
What sphincter connects to the large intestine?
Ileocecal valve
28
What happens in the large intestine?
undigested particles are fermented by bacteria
29
What happens if there is a micrbiome imbalance
Diarrhea, constipation and obesity
30
What is a probiotic
Bacteria in foods that is needed to increase the intestinal micro biome ie. fermented milk, veggies
31
What are prebiotics
promotes growth of good bacteria
32
Synbiotics
mix of pro and pre - viability of colon
33
What does the lymphatic system do
- transports fat soluble proteins - returns fluid back to blood - transports lipoproteins
34
What are the four types of lipoproteins
chylo VLDL LDL HDL
35
Describe the lifecycle of lipoproteins
as chylo circulates, cells remove lipid contents liver reassembles them into diff lipoproteins becomes VLDL triglycerides are removed from VLDL, making it becomes LDL --> bad because cholesterol is being deposited into peripheral tissues cholest is packed into lipoproteins and HDL are made
36
Insulin vs Glucogen
?
37
Where are lipids store and what is the storage capacity
Adipose tissue | Unlimited, hypertrophy and hyperplasia
38
What happens when the stomach distends
decreased GI transit time
39
What happens when there is a bulk of insoluble fibre
increased GI transit time
40
What do g cells do
Secrete Gastrin, increased gastrin increases gastric acid
41
Gastrin feedback system
pH over 5 = released | ph less 3 = inhibited
42
Secreten stimulates and purpose for that is?
the pancreas to release sodium bicarb to neutralize chyme
43
secretin feedback loop
under ph 4.5 = released | over 4.5 = inhibited
44
What is CCK used for
- release bile for fat digestion | - reduces feelings of fullness
45
feedback for cck
lipid rich chyme = released | lipid poor chyme = inhibited
46
purpose of Gastric inhibitory peptide (GIP)
Stimulates insulin secretion
47
feedback for gip
hyperosmotic chyme = released | hypo = inhibited