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Neuro > Diffuse Modulatory Systems > Flashcards

Diffuse Modulatory Systems Flashcards

1
Q
  1. Name & ID the midbrain nuclei in the dopaminergic diffuse modulatory system
A

VTA & Pars Compacta

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2
Q

1a. What dopaminergic nucleus projects axons to the dorsal striatum?

A

pars compacta

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3
Q
  1. name & ID the axonal specializations for extrasynaptic release of neurotransmitter
A

varicosities

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4
Q

2a. what part of the neuron contains the dopamine reuptake transporters in classical & extrasynaptic neurotransmitter communications?

A

varicosity for diffuse system & synaptic bulb for classic system

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5
Q
  1. name & id the hypothalamic locus of cell bodies for the histaminergic diffuse modulatory system
A

tubolomandibular nucleus in hypothalamus

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6
Q

3a. does histaminergic stimulation of H1 receptors enhance or inhibit wakefeulness & attention

A

enhance wakefulness & attention; antihistamines inhibit them & make them drowsy

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7
Q
  1. Name & ID nuclei that contribute to acetylcholinergic diffuse modulatory system
A

medial septal nuclei
basal nucleus of meynart
lateraldorsal tegmental nucleus
pedunculopontine nucleus

(lateraldorsal tegmental nucleus + pedunculopontine nucleus = pontomesencephalotegmental complex)

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8
Q

4a. What acetylcholinergic complex projects axons to the reticular formation to initiate muscle atonia during REM sleep?

A

the one in the midbrain: lateraldorsal tegmental nucleus & pedunculopontine nucleus

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9
Q
  1. name & id structures constituting epithalamus
A

pineal gland, habeular nuclei (medial & lateral)

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10
Q

5a. what fiber bundle conveys acetylcholinergic fibers from septal nuclei to habenular nuclei?

A

stria medularis

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11
Q
  1. name & id nuclei that constitute serotoninergic diffuse modulatory system
A

raphe nuclei

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12
Q

6a. do enkephalinergic interneurons mediate serotonin’s inhibitory or its stimulatory effect on pain transmission in dordsal horn of spinal cord?

A

inhibitory, since it is often gabinergic

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13
Q
  1. name midbrain nucleus that acts as an intermediate integration center for medial habenular projection to raphe nuclei
A

interpeduncular nucleus

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14
Q

7a. what fiber bundle conveys habenular axons to interpeduncular nucleus?

A

fasciculus retroflexus

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15
Q
  1. name & id principle nucleus of noadrenergic diffuse modulatory system
A

locus coeruleus

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16
Q

8a. what adrenergic receptor is activated in spinal dorsal horne neurons by descending fibers originating in locus coeruleus to suppress pain transmission

A

alpha 2 receptor

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