Differentials 2.0 Flashcards
S4
Sound made by atria filling hypertrophic ventricle causing turbulent flow, always abnormal
Left ventricular hypertrophy
Aortic stenosis
HTN
CAD
Cardiomyopathy
Cyanosis
Adult: Drug intoxication, choking, brain injury, cystic fibrosis, PE, high altitude
Child: Obstructed airway, asthma, RSV, Tetralogy of Fallot, hypothermia, seizure
Developmental Delay
Trisomy 21, toxins (drugs, fetal alcohol), autism, malnourished/neglect, brain tumor, cerebral palsy
Anxiety
OCD, social anxiety, GAD, panic disorder medications, separation
Upper GI Bleed
Adult: Epistaxis, esophageal varices, neoplastic, MW tear, ulcer
Child: Gastritis, ulcers, varices, coagulopathy
Abdominal/Pelvic Mass
Adult: Hepatocellular carcinoma, splenomegaly, appendicitis, fibroids, polycystic kidney, hepatitis, AAA
Child: Fecal impaction, intussusception, kidney, neoplastic (Wilm’s, renal cell carcinoma)
Diarrhea
Adult: Drugs/medication, food intolerance/dietary, IBS, C. dif, carcinoid tumor
Child: Food intolerance, laxatives, infections, medications, malabsorption
Constipation
Adult: Low fiber intake, neoplasm (colorectal cancer), pregnancy, drugs, hernia
Child: Diet, medication, cystic fibrosis, psychological, Hirschsprung’s
Diplopia
Adult: Stroke, brain tumor, cataracts, Bell’s palsy, CN palsy, traumatic, HTN, dislocated lens
Child: Strabismus, intracranial mass, thyroid abnormality, keratoconus, refractive error
Dizziness/Vertigo
Adult: Refractive error, benign paroxysmal positional vertigo, Meniere’s, neuronitis, zoster, stroke
Child: Ear infection, head trauma, acoustic neuromas, MS, panic disorder, seizures
Hypotension
Adult: Hemorrhage, heart failure, pneumothorax, aortic dissection, AAA, substance abuse
Child: Anaphylaxis, shock, drugs, Addison’s, dehydration
Dying Patients
- Palliative Care
- Communication
- Pronouncing death
- End of life directives and substitute decision maker
Dysphagia
Adult: Achalasia, neoplasm, neuromuscular (stroke), reflux, structural (Zenker’s, tumor, strictures)
Child: Mechanical obstruction, neoplasm, cleft lip/palate, swallowing disorders
Dyspnea
Adult: Lung cancer, asthma, COPD, PE ,CHF, MI, toxins
Child: Asthma, mechanical obstruction, panic attack/hyperventilation, anemia, CF
Ear Pain
Adults: TMJ, sinusitis, trauma (frost bite piercing), otitis media/externa, trigeminal neuralgia
Child: Otitis media, trauma, foreign body, abscess, cerumen impaction
Early Pregnancy Loss/Spontaneous Abortion
Drugs/toxins, chromosomal abnormality, PCOS, ectopic pregnancy, coagulopathy, uterine abnormalities
Edema (generalized)
Adult: Heart failure, nephritic syndrome, DVT, cirrhosis, pregnancy
Child: Nephritic syndromes, allergy, malnutrition, medication, cardiac failure, thyroid disorders
Hemoptysis
Adult: MW tear, AAA, lung infection, lung cancer, PE, TB
Child: Trauma, foreign body, AVM, bacterial pneumonia
Edema (Localized)
Adult: DVT, injury, infection, lymphedema
Child: Infection, injury, inflammation, allergy
Lower GI Bleed
Adult: Anorectal disease, colorectal cancer, trauma, enterocolitis
Child: C. dif, Hirschsprung’s, allergy, anal fissure
Erectile Dysfunction
Depression, alcohol, medications, drugs, diabetes
Eye Redness
Adult: EKC, corneal ulcer, bacterial infection, HSV keratitis, iritis, glaucoma
Child: Traumatic (eye rubbing), adenovirus, GPC, foreign body, blepharitis
Frailty in the Elderly
Dementia, delirium, medication, social (isolation, poverty, elder abuse), malnutrition, visual/auditory change, mobility
Breast Discharge
Prolactinoma, lactation, medication induced galactorrhea, mastitis, duct papilloma
Abdominal Distention
Adult: Hepatomegaly, fibroids, AAA, pregnancy, IBS, constipation, H pylori, bowel obstruction
Child: Volvulus, trauma, allergic, dietary, bowel obstruction
Failure to Thrive (infant)
Malnutrition, poor prenatal care, neglect, feeding problems (cleft lip/palate, malabsorption
Falls
Vertigo, syncope, malnutrition, decrease vision, choice of footwear, medication
Calcium Disorder
Adult: Renal insufficiency, hypoparathyroidism, malignancy, vitamin d deficiency
Child: Poor nutrition, malabsorption, medications
Abdominal Pain
Adult: Ulcer, appendicitis, colic, gastroenteritis, cholecystitis, pancreatitis
Child: Bowel obstruction, pyelonephritis, dietary, appendicitis
Fatigue
Adult: Malignancy, anemia, depression, stress, hypothyroid
Child: Psychosocial (poverty, poor living conditions, abuse), anemia
Genetic Concerns
Chromosomal, prenatal exposure, neural tube defects, auto dom/rec
Congenital Anomalies (Dysmorphic Features)
Trisomy 21, Turner’s, Fragile X, fetal alcohol, hypothyroidism
Glucose Abnormality
Adult: Diabetes, dehydration, diet, DKA, obesity, adrenal insufficiency, medication
Diabetes Mellitus
Type 1: autoimmune, idiopathic
Type 2: obesity, genetic, iatrogenic (medications)
Gestational: pregnancy
Headache
Adult: Migraine, tension, cluster, temporal arteritis, medication overuse, glaucoma, subarachnoid hemorrhage, carbon monoxide
Child: Meningitis, traumatic hemorrhage, medication, sinusitis, eye strain, post concussion
Health and Climate Crisis
Heat
Malnutrition
Infectious disease
Refugee and immigrants
Physical/social consequences
Contraception
Hormone
Barrier
IUD
Abstinence
Sterilization
Health of Special Populations
Homeless
Disabled
Immigrants
Poverty
Hearing Loss
Adult: Aging, cerumen, otitis media/externa, Meniere’s, medication (streptomycin, gentamycin, ASA)
Child: Foreign body, inner ear infection, perforation of tympanic membrane, vitamin deficiency, Alport’s
Cardiac Arrest
Adult: Coronary artery disease, conduction abnormalities, myocardial abnormalities, PE, hypothermia
Child: Structural abnormalities (Marfan’s, congenital), respiratory (pneumonia, bronchiolitis), infection (sepsis, meningitis), traumatic child abuse
Hemoglobin (Anemia)
Normocytic: cell loss, cell destruction, decreased production, chronic disease
Microcytic: iron deficiency, hemoglobinopathies
Macrocytic: vitamin b12 or folate deficiency, alcohol abuse
Hemoglobin Elevation
Elevated EPO (hypoxemia, EPO secreting tumor)
Decreased plasma volume
Polycythemia vera
Hypothermia management
- Severity
- Precipitating events
- Life saving measures
- Long term treatment plan
- Active vs passive rewarming
- Need for specialized care
Urinary Incontinence
Adult: Dementia, UTI, stress, cystitis, outflow obstruction, immobility
Child: Anxiety, delayed development, UTI, diabetes
Fecal Incontinence
Adult: Cauda equina, rectal prolapse, colorectal cancer, IBS
Child: Anxiety, dietary, neurological
Indigenous Health
- Demonstrate awareness of root cause of inequitable health care and outcomes experienced by Indigenous Peoples
- Provide anti-racist and culturally appropriate care
- Describe health services delivered to IP
- Four key themes of United Nations Declaration on the Rights of Indigenous people (right to self-determination; right to cultural identity; right to free, prior and informed consent; and the right to be free from discrimination)
Immunizations
- Assess immunization status
- Recommend appropriate schedule
- Counselling
- Contraindications
- Special at risk groups
Jaundice
Adult: Hepatitis, alcoholic cirrhosis, gallstones, pancreatic carcinoma, hepatic carcinoma
Child: Hemolytic, Gilbert’s, hypothyroid, infection, biliary atresia
Back Pain
Adult: Muscle strain, disc herniation, vertebral fractures, cancerous metastasis, vertebral osteomyelitis, seronegative spondyloarthropathies, pancreatitis, AAA
Child: Trauma (falls, abuse), malingering, neoplastic mass
Ataxia
Adult: Neurological disorder (Parkinson’s, multiple sclerosis), traumatic, osteoarthritis, disc herniation, head injury, alcohol
Child: Neurological (cerebral palsy), stroke, toxins, neoplastic, vitamin b12 deficiency
Neck Pain
Adult: Disc herniation, muscle strain, whiplash, fracture, neoplasm, arthritis
Child: Meningitis, mumps, neoplasm, arthritis
Chest Pain
Adult: MI, angina, asthma, pneumothorax, drugs/toxins, GERD, costochondritis, shingles, AAA
Child: Stress/anxiety, hyperventilation, cardiac abnormality, fractured rib
Joint Pain - Non-Articular Musculoskeletal Pain (pain in the muscles but not the joints)
Adult: Multiple sclerosis, overuse, depression, polymyalgia rheumatica, medications (statins), fibromyalgia
Child: Vitamin D deficiency, Guillan Barre, hypothyroid, connective tissue disorder (SLE, RA, PAN, etc)
Joint Pain - Oligoarthralgia (pain in 1-4 joints)
Adult: Ankylosing spondylitis, osteoarthritis, osteoporosis, RA, psoriatic arthritis, hepatitis, giant cell arteritis, gout
Child: Rubella, connective tissue disease (SLE, PAN), spondyloarthropathies (AS, juvenile arthritis, Reiter’s), sickle cell
Coagulation Abnormalities
Adult: VWB, medication, cancer, traumatic (abrasion, laceration), platelet disorder
Child: Hemophilia A/B, vitamin deficiency, neoplastic, epistaxis
Coagulation Abnormalities
Adult: VWB, medication, cancer, traumatic (abrasion, laceration), platelet disorder
Child: Hemophilia A/B, vitamin deficiency, neoplastic, epistaxis
Joint Pain - Polyarthralgia (pain in more than 4 joints)
Adult: RA, osteoarthritis, fibromyalgia, polymyalgia rheumatica, septic arthritis
Child: Juvenile polyarthritis, SLE, fractures
Language and Speech Disorders
Adult: Head injury, Parkinson’s, loss of hearing, stroke, neck neoplasms
Child: Stuttering, deafness, autism, neglect/abuse, cleft lip/palate
Legal, Ethical and Organizational Aspects of Medicine - Confidentiality
- Know what the exceptions are
- Who to release information to
- Mandatory disclosures
- Limitations
- Alternate decision makers
Legal, Ethical and Organizational Aspects of Medicine - Consent
- How to obtain informed consent
- Know steps to take for substitute decision makers
- Implied consent
- Issues with verbal/written consent
- Identify information that must be provided
Legal, Ethical and Organizational Aspects of Medicine - Legal System
- Federal vs provincial statutes
- Regulatory bodies
- Awareness of when consultation is important
Legal, Ethical and Organizational Aspects of Medicine - Negligence
- Elements required to prove negligence
- Differences in standard of care based on health care provider
- Appropriate communication with patient
- CMPA
Legal, Ethical and Organizational Aspects of Medicine - Truth Telling
- Communicate effectively
- Identify challenging situations and how to best address them
- Ascertain personal/cultural context of patient or professional
- Recognize when it is necessary to disclose personal beliefs or values that could be in conflict with patient choices
Limp in Children
Abuse, trauma, neuromuscular disorders, bone deformity, referred pain, tumor
Lump/Mass (Musculoskeletal)
Benign: Lipoma, epidermoid cysts, osteomyelitis, hematoma, rheumatoid nodules, granuloma
Malignant: sarcomas (leiomyosarcoma, Ewing’s sarcoma)
Lymphadenopathy (submandibular, axillary or inguinal nodes that are abnormal in either size, consistency or number)
Localized:
Strep (look for tender cervical nodes, sore throat)
Mononucleosis (symmetric adenopathy, usually cervical but sometimes axillae or inguinal)
Skin and soft tissue infection (cat scratch, cellulitis, etc look for erythema and tenderness of isolated node)
TB (cough)
Kawasaki (tender cervical nodes in children)
Generalized:
Idiopathic
Neoplastic (painless adenopathy, look for fever and weight loss)
HIV (look for fever, malaise, rash)
SLE (look or malar rash, arthritis)
Sarcoidosis (look for cough, muscle weakness, weight loss, could also be localized)
Mediastinal Mass
Adult: Thymoma, lymph nodes, esophageal abnormalities, cardiac tumor
Child: Ectopic thyroid, teratoma, lymphadenopathy, meningomyelocele, cystic hygroma
Menopause
12 months of amenorrhea
Give HRT for symptom control of hot flashes (beneficial effects on bone mineral density but increases risk of breast cancer after 5-7 years)