Differential & Work-up: Fatigue & Sleepiness, Night Sweats Flashcards
40 yo F c/o feeling tired, hopeless, and worthless and of having suicidal thoughts. She lost her job and has been having fights with her husband about money.
- Depression
- Adjustment disorder
- Hypothyroidism
- Anemia
WORK UP FOR:
- Depression
- Adjustment disorder
- Hypothyroidism
- Anemia
- PHQ-9
- Beck Depression Inventory
- TSH
- CBC
44 yo M presents with fatigue, insomnia, and nightmares about a murder that he witnessed in a mall 1 year ago. Since then, he has avoided the mall and has not gone out at night.
- Post-traumatic stress disorder
- Depression
- Generalized anxiety disorder
- Psychotic or delusional disorder
- Hypothyroidism
WORK UP FOR:
- Post-traumatic stress disorder
- Depression
- Generalized anxiety disorder
- Psychotic or delusional disorder
- Hypothyroidism
- PHQ-9
- Beck Depression Inventory
- CBC
- TSH
- Urine toxicology
55 yo M presents with fatigue, weight loss, and constipation. He has a family history of colon cancer.
- Colon cancer
- Hypothyroidism
- Renal failure
- Hypercalcemia
- Depression
WORK UP FOR:
- Colon cancer
- Hypothyroidism
- Renal failure
- Hypercalcemia
- Depression
- Rectal exam with stool guaiac test
- CBC
- CMP
- TSH
- Colonoscopy
- Barium enema
- CT -abdomen/pelvis
40 yo F presents with fatigue, weight gain, sleepiness, cold intolerance, constipation, and dry skin.
- Hypothyroidism
- Depression
- Diabetes
- Anemia
WORK UP FOR:
- Hypothyroidism
- Depression
- Diabetes
- Anemia
- TSH, FT 3, FT 4
- CBC
- Fasting glucose
- HbA1c
50 yo obese F presents with fatigue and daytime sleepiness. She snores heavily and naps 3 to 4 times per day but never feels refreshed. She also has hypertension.
- Obstructive sleep apnea
- Hypothyroidism
- Chronic fatigue syndrome
- Narcolepsy
WORK UP FOR:
- Obstructive sleep apnea
- Hypothyroidism
- Chronic fatigue syndrome
- Narcolepsy
- CBC
- TSH
- Nocturnal pulse oximetry
- Polysomnography
- ECG
20 yo M presents with fatigue, thirst, increased appetite, and polyuria.
- Diabetes mellitus
- Atypical depression
- Primary polydipsia
- Diabetes insipidus
WORK UP FOR:
- Diabetes mellitus
- Atypical depression
- Primary polydipsia
- Diabetes insipidus
- HbA1c
- Glucose tolerance test
- UA
- CBC
- Electrolytes, BUN/Cr, fasting glucose
35 yo M policeman c/o feeling tired and sleepy during the day. He changed to the night shift last week.
- Shift work sleep disorder
- Sleep apnea
- Depression
- Anemia
WORK UP FOR:
- Shift work sleep disorder
- Sleep apnea
- Depression
- Anemia
- CBC
- Nocturnal pulse oximetry
- Polysomnography
30 yo M presents with night sweats, cough, and swollen glands of 1 month’s duration. He recently emigrated from the African subcontinent.
- Tuberculosis
- Acute HIV infection
- Lymphoma
- Leukemia
- Hyperthyroidism