Differential & Work-up: Amennorhea, Abuse Flashcards
40 yo F presents with amenorrhea, morning nausea and vomiting, fatigue, and polyuria. Her last menstrual period was 6 weeks ago. Her breasts are full and tender. She uses the rhythm method for contraception.
- Pregnancy
- Anovulatory cycle
- Hyperprolactinemia
- UTI
- Hypothyroidism
WORK UP FOR:
- Pregnancy
- Anovulatory cycle
- Hyperprolactinemia
- UTI
- Hypothyroidism
- Urine hCG
- Pelvic exam
- U/S-transvaginal
- CBC
- UA, urine culture
- Prolactin, TSH
- Baseline Pap smear, cervical cultures, rubella antibody, HIV antibody, HBs Ag, VDRL/RPR
23 yo obese F presents with amenorrhea for 6 months, facial hair, and infertility for the past 3 years.
- Polycystic ovary syndrome
- Thyroid disease
- Hyperprolactinemia
- Pregnancy
- Ovarian or adrenal malignancy
- Premature ovarian failure
WORK UP FOR:
- Polycystic ovary syndrome
- Thyroid disease
- Hyperprolactinemia
- Pregnancy
- Ovarian or adrenal malignancy
- Premature ovarian failure
- Pelvic exam
- Urine hCG
- Transabdominal & transvaginal ultrasound
- LH/FSH, TSH, prolactin
- Testosterone, DHEAS
35 yo F presents with amenorrhea, galactorrhea, visual field defects, and headaches for the past 6 months.
- Amenorrhea secondary to prolactinoma
- Pregnancy
- Thyroid disease
- Premature ovarian failure
- Pituitary tumor
WORK UP FOR:
- Amenorrhea secondary to prolactinoma
- Pregnancy
- Thyroid disease
- Premature ovarian failure
- Pituitary tumor
- Pelvic and breast exams
- Urine hCG
- LH/FSH, TSH, prolactin
- MRI-brain
48 yo F presents with amenorrhea for the past 6 months accompanied by hot flashes, night sweats, emotional lability. and dyspareunia.
- Menopause
- Pregnancy
- Pituitary tumor
- Thyroid disease
WORK UP FOR:
- Menopause
- Pregnancy
- Pituitary tumor
- Thyroid disease
- Pelvic exam
- Urine hCG
- LH/FSH, TSH, prolactin
- Testosterone, DHEAS
- CBC
- MRI-brain
35 yo F presents with amenorrhea, cold intolerance, coarse hair, weight loss, and fatigue. She has a history of abruptio placentae followed by hypovolemic shock and failure of lactation 2 years ago.
- Pituitary infarction (Sheehan syndrome)
- Premature ovarian failure
- Pituitary tumor
- Thyroid disease
- Asherman syndrome
WORK UP FOR:
- Pituitary infarction (Sheehan syndrome)
- Premature ovarian failure
- Pituitary tumor
- Thyroid disease
- Asherman syndrome
- ACTH
- Pelvic exam
- Urine hCG
- LH/FSH, prolactin
- CBC
- TSH, FT4
- MRI-brain
- Hysteroscopy
18 yo F presents with amenorrhea for the past 4 months. BMI is 14.5 kg/m2. She attends vigorous exercise classes frequently and has a history of heat intolerance.
- Anorexia nervosa
- Pregnancy
- Hyperthyroidism
WORK UP FOR:
- Anorexia nervosa
- Pregnancy
- Hyperthyroidism
- Urine hCG
- CBC
- Electrolytes
- TSH, FT4
- LH/FSH
29 yo F presents with amenorrhea for the past 6 months. She has a history of occasional palpitations and dizziness. She lost her fiance in a car accident in which she was a passenger.
- Anxiety-induced amenorrhea
- Pregnancy
- Posttraumatic stress disorder
- Depression
- Hyperthyroidism
WORK UP FOR:
- Anxiety-induced amenorrhea
- Pregnancy
- Posttraumatic stress disorder
- Depression
- Hyperthyroidism
- Urine hCG
- CBC
- TSH, FT4
- Urine cortisol level
- Progesterone challenge test
- LH/FSH, estradiol levels
28 yo F c/o multiple facial and bodily injuries. She claims that she fell on the stairs. She was hospitalized for physical injuries 7 months ago. She presents with her husband.
- Domestic violence
- Osteogenesis imperfecta
- Substance abuse