Differential Diagnosis: Red Lesions Flashcards

1
Q

What makes a red lesions red?

A
  • Decreased thickness of epithelium
  • Inflammatory dilation of blood vessels
  • Increased numbers of small blood vessels
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2
Q

What is the most common oral form of Candida seen in the dental office?

A

Denture Stomatitis

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3
Q

What are things that can cause Angular Chelitis? (4)

A
  • Overclosure
  • Candidiasis
  • Vitamin B Complex Deficiency
    • Except thiamine B1
  • Iron Deficiency
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4
Q

What is the Differential Diagnosis for a red, atrophic, bald tongue? (4)

A
  • Xerostomia
  • Acute Atrophic Candidiasis = Antibiotic Sore Mouth
    • Scalded tongue sensation
    • Loss of filliform papillae
  • Vitamin B Complex Deficiency/Iron Deficiency
  • Resolving Benign Migratory Glossitis
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5
Q

What is the Differential Diagnosis for Red, Atrophic, Desquamative Gingivitis = shiny erythema generalized to gingiva and alveolar mucosa, sloughing? (4)

A

Differentiate with histo

  • Benign Mucous Membrane Pemphigoid
  • Lichen Planus
  • Pemphigus
  • Allergy/Hormonal
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6
Q

What in the Differential Diagnosis for Red, Atrophic, Desquamatic Gingivitis, has a histo of SUBepithelial clefting?

A

BMMP

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7
Q

What in the Differential Diagnosis for Red, Atrophic, Desquamatic Gingivitis, has a histo of: hyperORTHOkeratosis, saw-tooth rete ridges, with a dense, linear subepithelial infiltrate of lymphocytes?

A

Erosive Lichen Planus

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8
Q

What in the Differential Diagnosis for Red, Atrophic, Desquamatic Gingivitis, has a histo of: SUPRAbasilar vesicles, acantholytic cells?

A

Pemphigus

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9
Q

What in the Differential Diagnosis for Red lesions of the Palate?

A
  • Hemangioma
  • Kaposi’s Sarcoma
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10
Q

When diagnosising a red palatal lesion, what questions should you ask?

A
  • Has it been there pts entire life?
    • Hemangioma - stops at the midline
  • What is the pts HIV status?
    • Kaposi’s Sarcoma
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11
Q

What is the Differential Diagnosis for Red and White Lesions? (5)

A
  • Amalgam Allergy
    • Sulfur products
  • Aspirin Burn
    • White when epithelium is present and red when it sloughs off
  • Candidiasis
    • Palatal, related to steroids and dentures
  • Cinnamon Reaction
    • Unilateral: buccal mucosa + tongue = kissing lesions
    • Hurts, burns
  • Lupus
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12
Q

What is the Differential Diagnosis for Asymptomatic Red Lesions on the Palate? (7)

A
  • Non-specific irritation
  • Candidiasis
  • CIS/SCC
  • Allergy
  • Lichen Planus
  • Lupus
    • ​Loves the palate and lips
  • Benign Migratory Stomatitis
    • Kissing lesion
    • Well demarcated erythmatous area surrounded by a white border
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13
Q

What is the Differential Diagnosis for Chronic, Burning Lesion on the Cheek? (5)

A
  • Lichen Planus
  • Cinnamon Stomatitis
  • Candidiasis
  • Dysplasia/CIS/SCC
  • Lupus
    • Looks like LP in the mouth but the pt has the butterfly rash on their face
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14
Q

What are the many faces of Candidiasis? (5)

A

“MAP of DC”

  • Median Rhomboid Glossitis
  • Angular Chelitis
  • Pseudomembranous Candidiasis
  • Denture Sore Mouth
  • Chronic Hyperplastic Candidiasis
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15
Q

In which type of Candidiasis does the white part scrape off, revealing an erythematous non-bleeding surface?

A

Pseudomembranous Candidiasis

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16
Q

What type of Candidiasis is most often found in smokers?

A

Median Rhomboid Glossitis

17
Q

What type of Candidiasis is common in Diabetics?

A

Chronic Hyperplastic Candidiasis

  • Bilateral corner of lips like in Angular Chelitis
  • May be indurated
18
Q

What are the Systemic Causes of Candidiasis? (5)

A

“AIDS X-ills”

  • Antibiotic Therapy
  • Immunosuppressive Disease
    • HIV
    • Malignancy (Leukemia, Lymphoma, Myeloma)
  • Diabetes
  • Steroids
  • Xerostomia - from any cause
    • Radiation/Chemo
    • Sjogren Sx, Autoimmune Diseases
19
Q

What are the Local Causes of Candidiasis? (4)

A

“Lucky to get my DMD”

  • Lichen Planus
    • Candida loves to grow in LP
  • Dentures
    • Angular Cheilitis from overclosed VDO
    • DSM, Papillary Hyperplasia
  • Median Rhomboid Glossitis
  • Dysplasia
20
Q

What are the Clinical Lichenoid Lesions? (7)

A

“GLAD lichenoid lesions are in the ACC”

  • Graft vs. Host Disease
  • Lupus
  • Antihypertensives
  • Dysplasia/CIS
  • Amalgam Hypersensitivity
  • Candida
  • Cinnamon Reaction
21
Q

How long can it take for a lichenoid lesion to appear due to Antihypertensives?

A

Can take up to 2 years of being on the medication for Lichen Planus to show up.

22
Q

How long can it take for a lichenoid lesion caused by Antihypertensives to disappear?

A

Can take up to 1 year before the lichenoid lesion will go away, you can’t just take people off their HTN meds

23
Q

What is the Diagnostic Histology of the Cinnamon Reaction?

A

Perivascular Infiltrate

24
Q

What is the Histology of Dysplasia? (4)

A
  • Keratin present = white lesion
  • Dysmaturation - jumbled appearance of cells in the lower portion of the epithelium
  • Tear Drop Rete Ridges
  • Hyperkeratosis, mature surface cells, deeper cells show dysmaturation, dyskeratosis (squamous pearls), hyperchromatism, pleomorphism
25
Q

What is the Histology of CIS?

A
  • No Keratin = Red lesion
  • Full thickness/top to bottom shows:
    • Large, crowded, immature cells
    • No maturation