Differential Diagnosis: Premature Loss of Teeth

Question 1

• No cementum on roots for PDL to attach, can’t hold the teeth in
• Unexplained loss of deciduous teeth

Answer 1

Hypophosphatasia

Question 2

What is the Diagnostic Blood Test for Hypophosphatasia?

Answer 2

• Decreased alkaline phosphatase
• Increased urinary ethanolamine

Question 3

• No or short roots
• Crowns look normal
• Little of no detectable pulp

Answer 3

Dentinal Dysplasia Type I

Question 4

What is the etiology of Dentinal Dysplasia Type I?

Answer 4

Autosomal Dominant

Question 5

Pulp horns that go up to DEJ - easily exposed during preparation.

Answer 5

Vitamin D Resistant Ricketts

“Hypophosphatemia”

Question 6

What are the lab values for Hypophosphatemia?

Answer 6

Lowered serum phosphate

• kidney can’t absorb phosphate, so it leaks out and the bones can’t form normally

Question 7

What is the etiology of Vitamin D Resistant Ricketts?

Answer 7

X-linked Dominant

Males affected more severely

Question 8

• Rare form of external root resorption, starting at the CEJ
• Crown of tooth falls off

Answer 8

Idiopathic Multiple Cervical Resorption

Question 9

What population is affected by Idiopathic Multiple Cervical Resorption?

Answer 9

Young, healthy, females

Question 10

What condition causes the premature lose of deciduous teeth and the early eruption of permanent teeth?

Answer 10

Hyperthyroidism

Question 11

• Characteristic oral ulcerations, with severe bone loss, gingival recession and tooth mobility

Answer 11

Agranulocytosis Neutropenia

Question 12

• Accelerated periodontitis due to neutrophil dysfunction
• Hyperkeratosis of palms and soles

Answer 12

Papillon Le-Fevre Sx

Question 13

What is the inheritence pattern of Papillon Le-Fevre Sx?

Answer 13

Autosomal Recessive

Question 14

What periodontal problems are associated with Scurvy?

Answer 14

Swollen, extremely hemorrhagic gingiva, with loose teeth