Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Ultimate Brand Generic > dibetes > Flashcards

dibetes Flashcards

1
Q

Biguanide

A

works primarily by decreasing hepatic glucose production. Also decreases instestinal absorption of glucose and improves insulin sensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Glucophage, XR, Fortamet, Glumetza

A

decrease A1C 1-2%, BBW: lactic acidosis, C/I: men Scr>=1.5, female >=1.4, Crcl < 60, caution in heart failure if worsening hold metformin, SE: NVD, flatulence, B12 deficiency, NO hypoglycemia, hold iodinated contrast dye for 48 hours, decrease in B12 absoroption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Metaglip

A

metformin + glipizide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Glucovance

A

metformin + glyburide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Actoplus Met

A

metformin + pioglitazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Avandamet

A

metformin + rosiglitazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Janumet, XR

A

metformin + sitagliptin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Kombiglyze, XR

A

metformin + saxagliptin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Jentadueto

A

metformin + linagliptin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

PrandiMet

A

metformin + repaglinide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Sulfonylureas

A

work by stimulating insulin secretion from the pancreatic beta cells. Do not use with meglitinides due to similar MOA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Diabinese

A

chlorpropamide, SE hypoglycemia, weight gain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Older sulfonylureas no longer used

A

acetohexamide, tolazamide, tolbutamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Glucotrol, XL

A

glipizide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Amaryl

A

glimepiride

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Duetact

A

glimepiride + pioglitazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

DiaBeta

A

glyburide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Glynase PresTab

A

micronized glyburide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Meglitinides

A

work by stimulating insulin secretion from the pancreatic beta cells. Do not use with sulfonylureas due to similar MOA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Prandin

A

repaglinide SE:hypoglycemia, weight gain, URTI, gemfibrozil increases prandin concentration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Starlix

A

nateglinide

22
Q

Thiazolidinediones (TZDs)

A

are peroxisome proliferator-activated receptor gamma agonist causing increase peripheral insulin sensitivity, increase uptake and utilization of glucose by the peripheral tissue, insulin sensitizer

23
Q

Actos

A

pioglitazone, BBW: NYHA class 3 & 4 heart failure may exacerbate HF, do not use with active bladder cancer, SE: weight gain, CHF, peripheral & macular edema, increase fracture risk, increase LFTs

24
Q

Avandia

A

rosiglitazone, BBW: NYHA class 3 & 4 heart failure may exacerbate HF, SE: weight gain, CHF, peripheral & macular edema, increase fracture risk, increase LFTs

25
Q

Avandaryl

A

rosiglitazone + glimepiride

26
Q

Alpha-glucosidase inhibitors

A

inhibit alpha glucosidase in the intestines resulting in delayed absorption of glucose. Also inhibit metabolism of sucrose to glucose and fructose. Inhibits pancreatic nz which delay the digestion of starch

27
Q

Precose

A

acarbose, with first bite of each main meal, CI: IBD, colonic ulceration, intestinal obstruction, SE: GI effects, good: increase HDL, and decrease TG & total cholesterol

28
Q

Glyset

A

miglitol, with first bite of each main meal, CI: IBD, colonic ulceration, intestinal obstruction, SE: GI effects, good: increase HDL, and decrease TG & total cholesterol

29
Q

DDP4 inhibitors aka incretin enhancers

A

dipeptidyl peptidase IV inhibitors prevent the enzyme DPP4 from breaking down incretin hormones, glucagon like peptide-1 (GLP1) and glucose dependent insulinotropic polypeptide. These hormones help to regulate blood glucose by increasing insulin release from the pancreatic beta cells and decreasing glucagon secretion from pancreatic alpha cells. A reduction in glucagon results in decreased glucose production.

30
Q

Januvia

A

sitagliptin, SE: weight neutral

31
Q

Juvisync

A

sitagliptin + simvastatin

32
Q

Onglyza

A

saxagliptin

33
Q

Tradjenta

A

linagliptin

34
Q

Glucagon like peptide 1 (GLP1) Agonist aka incretin mimetics

A

analogs of glucagon-like peptide-1 which increase insulin secretion and decrease glucagon secretion, slow gastric emptying, improve satiety, and may result in weight loss

35
Q

Byetta

A

exenatide, warning: pancreatitis, SE: nausea, avoid Crcl < 30 , SC

36
Q

Bydureon

A

exenatide ER, bbw: hx or FH of medullary thyroid carcinoma, warning: pancreatitis, SE: nausea, avoid Crcl < 30, SC

37
Q

Victoza

A

liraglutide, can be used as mono or combo, SC

38
Q

Pramlinitide MOA

A

synthetic analog of the human neuroendocrine hormone, amylin which is produced by pancreatic beta cells to assist in postprandial glucose control. Amylin helps slow gastric emptying and prevents an increase in serum glucagon following a meal and increases satiety. This is a amylinomimetic agent

39
Q

Symlin

A

pramlinitide, BBW: coadminister w insulin may cause hypoglycemia, SE: hypoglycemia, nausea, anorexia, Administer SC abdomen or thigh prior to each meal, comes in pen or vial and can be used in DM 1 & 2

40
Q

Bile Acid Binding Resins MOA

A

resins work by binding bile, blocking reabsorption. Bile is produced from cholesterol and cholesterol levels decrease.

41
Q

Welchol

A

colesevelam, CI: bowel obstruction

42
Q

Rapid Acting Insulin

A

aspart, glulisine, lispro

43
Q

Novolog, Novolog FlexPen

A

aspart

44
Q

Apidra, Apidra SoloStar

A

glulisine

45
Q

Humalog, Humalog KwikPen

A

lispro

46
Q

Humulin R, Novolin R

A

Regular, short acting insulin

47
Q

Humulin N, Novolin N

A

NPH, intermediate acting

48
Q

Long Acting insulin

A

detemir, glargine

49
Q

Levemir, Levemir FlexPen

A

detemir

50
Q

Lantus, Lantus SoloStar

A

glargine

Ultimate Brand Generic (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions