Diarrhoea Flashcards
What are 3 main classifications for diarrhoea?
Acute infective
Persistent
Chronic
6 types of acute infective diarrhoea
Watery Dysentery Mucoid Antibiotic-associated Parenteral Travellers'
Causes of watery/mucoid diarrhoea
Enterotoxin associated: - Cholera toxin - E. Coli Cytotoxin associated: - Shiga-like toxin Viral: - Rotavirus - Adenovirus Parasite-associated - Giardia Unknown mechanism: - Anaerobes
Causes of dysentery/mucoid diarrhoea
Invasive bacteria e.g. Shigella, Salmonella, Campylobacter
Parasites
Causes of antibiotic-associated diarrhoea
Clostridium difficile becomes pathogenic when other gut bacteria are eliminated
4 general categories of chronic diarrhoea
Malabsorption syndromes
IBD
Immunocompromised
Irritable bowel syndrome
Factors that can cause malabsorptive diarrhoea include:
Luminal factors
Mucosal factors
Interference with vascular & lymphatic drainage
Pancreatic & biliary deficiency
Primary malabsorption syndrome: tropical sprue