diarrhoea

Question 1

what are the 6 classes of drugs used to treat diarrhoea?

Answer 1

acute:
(1) Opioid Agonists
(2) Colloidal Bismuth Compounds
(3) Intestinal Adsorbents (e.g., Kaolin and Pectin)
(4) Bismuth
chronic:
(5) Bile Salt-Binding Resins
(6) Somatostatin-like Peptides
(7) Products of Lactobacillus acidophilus

Question 2

name an example of opioid agonist

Answer 2

loperamide

Question 3

what is the MOA for loperamide?

Answer 3

first line for rapid symptomatic relief
increases colonic transit time

Question 4

what are the adverse effects associated with loperamide?

Answer 4

cns effects - addiction and abuse
risk of cardiac abnormalities on OVERDISE of loperamide

Question 5

what are the adverse effects associated with bismuth?

Answer 5

bismuth toxicity - resulting in encephalopathy

Question 6

name an example of intestinal adsorbents

Answer 6

diosmectite and kaolin

Question 7

what are the adverse effects associated with diosmectite?

Answer 7

should not be taken within 2h of other meds

Question 8

name an example of lactobacillus acidophilus

Answer 8

lacteol fort

Question 9

what are the adverse effects of lacteolfort

Answer 9

important to maintain hydration

Question 10

who cannot take lacteolfort

Answer 10

ppl who r lactose intolerant