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Pharm 2 > Diaminopyrimidines > Flashcards

Diaminopyrimidines Flashcards

1
Q

basic or acidic

A

basic

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2
Q

static or cidal

A

static

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3
Q

MOA?

A

binds and inhibits dihydrofolate reductase enzyme so no tetrafolate made

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4
Q

PharmKNX

A

oral and parenteral= great absorption EXCEPT SUBQ
GREAT concentration in CSF so good for brain infections.
also good for mastitis and prostrate compared to sulfs (because of ion trapping)

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5
Q

Metabolism

A

Oxidation and conjugation

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6
Q

Excretion

A

metabolites in the urine

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7
Q

DRUGS O.P.T.

A

Ormetoprim
Pyrimethamine
Trimethoprim

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Pharm 2 (6 decks)

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