Diagnostics Flashcards
Hertel exophthalmometry norms
Measuring proptosis
12-22mm for white pts
12-18mm for Asian
12-24mm for African
Abnormal if higher OR presence of >3mm asymmetry
Thyroid eye disease
Forced suctions to detect EOM restrictions
CT/MRI to detect enlargement of the EOMs (tendons will be spared)
Exophthalmometry to measure proptosis
Visual fields to detect optic n. Compression
Blood work (T3/T4/TSH)
Jones I test
Tests the patency of the nasolacrimal system. Fluorescein is instilled in the inferior fornix and should drain off the ocular surface within five minutes if the nasolacrimal system is functioning properly. Positive Jones I test = patent system. Fluorescein will be seen when pt blows nose or at back of patients throat.
Jones II test
Nasolacrimal irrigation with saline following a negative Jones I test (no fluorescein seen). Reflux of fluid through the same punctum indicates an obstruction within the upper or lower canaliculus. Retrograde flow through the opposite canaliculus and punctum indicates nasolacrimal blockage (other side of common canaliculus). If the pt tastes saline, performs a gag reflex, or if fluid is recovered from the nose, the obstruction has been cleared
Chocolate agar can dx which pathogens?
(also called Thayer-Martin agar)
Neisseria gonorrhoeae and Haemophilus influenzae
(“Hersheys and Nestle chocolate”)
How long does a full field ERG take?
up to 75 minutes
what does a reduced amplitude represent on ERG?
reduced number of functioning cells or cell death
what does delayed timing represent on ERG?
suggests sick or dysfunctional cells
what does EOG evaluate?
tests the outer retina and RPE, records light peak and dark trough
what is the Arden ratio?
light peak on EOG / dark trough on EOG, normal amount is > 1.85
what disease shows an abnormal EOG but normal ERG?
Best’s disease
what is full-field ERG?
objective test which uses diffuse stimulation of the entire retina to test retinal function, in both dark and light conditions
what does the a-wave on ERG represent
fast negative deflection by photoreceptors
what does the b-wave on ERG represent
slower positive large amplitude deflection by bipolar cells and some Muller
oscillatory potentials on ERG
amacrine cells
photopic fast flicker on ERG
cone photoreceptors
c-wave
subretinal/RPE response
PhNR (photopic negative response)
ganglion cells and axons
clinical use for ERG, which diseases would warrant ERG testing
RP, Birdshot chorioretinopathy, etc
how does a MF-ERG differ from normal ERG?
provides a topographic measure of retinal electrophysiological activity, measures different regions of retina
waveform for mfERG
N1: Receptor and bipolar cells (negative wave)
P1: Bipolar
(positive wave)
N2
Plaquenil toxicity on mfERG
decreased waveforms in perifoveal bullseye
pattern ERG
targets ganglion cell function, only from the macular region.
optic neuropathies, glaucoma, etc.
VEP
measures visual cortex (only undilated pupil electrode test)
N75, P100, N135
P100 should be >5uv
peak 90-110msec normal
CT is better for
bone and calcification (denser tissue looks white), emergent situations, ex. orbital fractures
PET scan is used for
analyzes metabolic activity of tissues, ex. cancer metastasis
MRI is better for
visualizing soft tissues