Diabets Insulin Flashcards
Who takes Insulin?
All Type 1
PREG
SURGERY
HIGH A1C
What insulins are long acting helps btwn meals?
BASAL
lower glucose by liver production btwn meals and overnight
lipid and protein synthesis
intermediate or long-acting
50 % of daily needs
What type of insulin controls hyperglycemia post meal?
BOLUS
stores nutrients)
Use rapid (best) or regular insulin
10-20 % of daily insulin requirement for each meal
Which insulin is immediate basal?
NPH- more frequent dosing
What are the other Long acting?
DOT GO!
Determir
Degludec
Glulisne- 1 daily. NO MIXING
Which bolus drug lowers risk of hypoglycemia and need to be taking 15min b4 meal?
RAPID
Lispro
Aspart
Glargine
LAG opposite of Rapid
What is the SHORT acting?
Regular insulin
What is the initiating steps for Insulin TYPE 1?
QD 0.4-0.5 u/kg/day
half as basal
half as bolus(divide by 3 meals.
What do you consider 1st, prior to Inuslin for DM2
GLP 1RA
Start BASAL insulin 10 units/day OR
0.1-0.2units / KG / day
.1 x 125= units
What is ideal for obese patient with A1C greater than >10%?
GLP-1 RA and BASAL insulin
What is next if A1c goal not met?
Consider GLP-1 OR
Add bolus/rapid insulin for 1 meal
start with 4 units QD
OR 0.1 units/kg
OR 10 % of basal
***ADD Bolus to meal if GOAL not met Q3mo
what are the goals for DM2 on insulin?
Pre meal/bedtime glucose 80-130
1-2 hr post-prandial <180mg/dl
How dose premixed insulin in DM2?
Switch to pre-mixed insulin BID
Divide current basal dose to 2/3 AM and 1/3 PM
or ½ AM ½ PM
Adjust dose by 1-2 units or 10-15% 1-2X/WK until SMBG target is reached
NEVER mix LONG TERM with…?
other insulins
LONG term pH level is off
MIXED ARE ONLY
BOLUS + INTERMEDIATE
When should pt on multiple insulins self monitor glucose?
Prior to meals and snacks Rarely post-prandially bedtime exercise suspect hypoglycemia critical tasks such as driving
When should A1c be tested?
MET goal-2x/year
NOT MET goal= 4x/yr
When should your insulin dose adjust?
Insulin log plus food/activity diary Based over several 7-14 days CHO should be consistent ONE change at a time small increments (10%) Adjust during earliest time of hyperglycemia
Basal insulin- check Fasting plasma glucose
Bolus insulin- check post prandial plasma glucose levels
How should you dose for Hypoglycemia?
2-4 units 10-20% related to that meal
<70 BG- alert
<54= clinically significant ED (ASY often)
<40- Symptomatic
<20- seizures, coma
Glucagon on tap- 1mg SC, 6.5 min response
RISK of INC HYPO- ELDERLY, RENAL,LIVER DZ, LONG HISTORY OF DM, INC PHYSICAL ACTIVITY, GASTROPARESIS, MEDS, ETOH
How do you dec affects of insulin d/t injection?
clean
Rotate injection site
LIPOhypertrophy- d/t fatty build up
What drugs should you stop with insulin?
any insulin increase RX
Sulfoureas, Non-sulfoureas (metGLITINIDES)
What should be on had for all on insulin?
15-20g CHO- candy
REpeat 15-20min
check BG
Still <60
Complex w/ protein
Check 15-20
15-15-15= no change seek ED
10g- orange juic 1/2 cup, grape juice, 2stp sugar, 5-6lifesavers
2 glucose tabs
What are BP goal for DM patients?
HIGHER CV risk
<130/80 mmHg
LOWER CV risk <140/90
What annual immunization are important?
Annual influenza vaccine
Pneumococcal vaccine
Ages 2-64 received PPSV23
Age >65 receive an additional PPSV23
Hepatitis B vaccine-3 dose