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3703 > Diabetic treatments > Flashcards

Diabetic treatments Flashcards

1
Q

Alpha Glucosidase inhibitor (OHA) mechanism of action

A
  1. Prevent intestinal breakdown of polysaccharides
  2. Reduce absorption of sugars
  3. Does not cause hypo on its own
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2
Q

Biguanides (OHA) mechanism of action

A
  1. Metformin
  2. Increases insulin sensitivity
  3. Reduces gluconeogenesis
  4. Does not cause hypos
  5. Causes weight loss
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2
Q

Biguanides (OHA) mechanism of action

A
  1. Metformin
  2. Increases insulin sensitivity
  3. Reduces gluconeogenesis
  4. Does not cause hypos
  5. Causes weight loss
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3
Q

Side effects of metformin

A
  1. Could cause lactic acidosis- avoid in renal, hepatic heart failure
  2. GI side effects
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4
Q

How does metformin cause lactic acidosis (renal metabolism)

A

The lactic acid is caused by intestinal non oxidative glucose metabolism

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5
Q

Sulfonylureas (SFUs) mechanism of action

A
  1. Stimulate B-cells to secrete insulin
  2. May reduce insulin resistance
  3. 1st, 2nd and 3rd generation
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6
Q

Side effects of sulfonylureas

A
  1. Flushing
  2. Hypos
  3. Weight gain
  4. Hyponatremia
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3703 (13 decks)

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