Diabetes Mellitis Flashcards
Why is insulin replacement necessary in T1DM?
Lack of insulin results in diabetic ketoacidosis and death within 48 hours
Hyperglycemia
Blood sugar is abnormally high
Hypoglycemia
Blood sugar drops below normal
What is a major risk associated with treatment of insulin?
Hypoglycemia
Can result in loss of consciousness, seizures, accidents, death
Insulin resistance and increased hepatic glucose production can contribute to the development of what?
Type 2 diabetes
What is the relationship between visceral fat and insulin resistance?
Higher the percentage of visceral fat the lower the insulin sensitivity
Various subtypes of T2DM provides what important information?
Pathophysiology and metabolic profile of T2DM is variable
Therapeutic management for T2DM includes what
Medications aimed to reduce risk of cardiovascular and renal diseases and lifestyle interventions
Which individuals receive insulin injections as a part of their treatment plan?
All T1DM and insulin-deficient T2DM
Why is it important for a physical therapist to know if the individual has had an eye exam?
Individuals with DM are at risk for retinopathy
Why does a physical therapist need to know about timing of insulin therapy and when were blood glucose levels last checked?
To know if a patient is at risk for hypoglycemia
Presentation of diabetic neuropathies
Varies and may involve pain, sensory loss, and motor loss
How is muscle affected in clinical progression of DM?
Decreases in mass and strength, increased fat, and connective tissue
Macrovascular complications of DM occur because of pathology in which blood vessels?
Atherosclerosis of medium and large vessels
Atherosclerosis
Build up of plaque in the arteries
Assessment of HA1c provides what important information?
Glycemic control over the past 3 months
Why are optimal HA1c levels and optimal blood pressure control critically important?
Slows progression of disease
Decreases risk of cardiovascular disease, retinopathy, and kidney disease
Improves quality of life
Microvascular complications of DM
Eye, kidney, and heart diseases
Macrovascular complications of DM
Heart, brain, and extremity diseases
Insulin resistance
Impaired biological response to insulin resulting in hyperglycemia and high circulating fatty acids