Diabetes Insipida Flashcards

1
Q

DI ( Diabetes insípida)

A
Poliuria hipotonica 
Vol orina > 50ml/kg/día; >3L
Osmolaridad urinaria <300mOsm
Osm plasm >290
Densidad urinaria <1.010
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2
Q

DI CENTRAL : falta de liberación de ADH

A

Tumores cerebrales o hipofisiarios; TCE; Qx hipotalamo hipofisiario; DI central familiar : AD, AVP- Neurofisina II
Sx Wolfram; Sx sheehan

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3
Q

DI NEFROGENICA

Ausencia de respuesta del riñón a la ADH

A

Causas

Litio, demeclociclina, NTA, genética o embarazo, hipoKalemia, hiperCalcemia

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4
Q

DI TX

A

Central: desmopresina
Nefrog: tiazidas, clorpropamida(sulfonilurea) o indometacina

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5
Q

SIADH

A

Hiponatremia hipotonica euvolemica
Hipernetriuresis por retención de agua
Disminución de aldosterona

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6
Q

SIADH

Causas

A

Malformaciones, paladar hendido, Ca pulmonar, TCE, tumor de secreción Ectopico

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7
Q

SIADH

Criterios dx

A

Na<135
Osm serica <275
Osm urinaria >100
Na u >30

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8
Q

SIADH

Tx

A

Corregir Na: soluc hipertonicas
Conivaptan
Furosemida
Demeclociclina

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9
Q

Acromegalia: adulto
Gigantismo: prepuber

A

Aumento de GH
Cara tosca, nariz grande, prognatismo
Dx falta de supresión de la Gh con carga de glucosa
Tx ocreotide ( anal somatostatina

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10
Q

Hiperaldosteronismo

Primario

A

Hipopotasemia ( produce inhibición de la secreción de insulina–> hiperglucemia )
; alcalosis metabólica; HTA
Causa: adenoma suprarrenal
Tx espironolactona o triamtireno

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11
Q

Hiperaldosteronismo

Primario: aumento de aldosterona no dependiente de renina : ausencia de edema

A

Secundario: elevación de aldosterona por aumento de la renina –> edemas

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