Diabetes Exam

Question 1

DM meds that increases insulin secretion

Answer 1

1. Sulfonylureas
2. Meglitinides
3. GLP-1 receptor antagonist
4. DPP-4 Inhibitor

Question 2

DM meds that improves insulin sensitivity (glucose transport) and decrease insulin resistance

Answer 2

1. Biguanides (Metformin)

2. Thiazolidinediones

Question 3

DM meds that restore/replicate incretin and increase insulin secretion and suppress glucagon secretion.

Answer 3

1. GLP-1 Agonist
2. DPP-4 inhibitors
3. Incretin mimetics

Question 4

DM meds that decrease the absorption of glucose.

Answer 4

1. Alpha-glucosidase Inhibitors

Question 5

Which medications can cause hypoglycemia?

Answer 5

1. Meglitinides
2. Sulfonylureas
3. GLP-I Analogs
4. D-phenylalanine

Question 6

Which medications cause GI upset?

Answer 6

1. AGI –> flatulence, diarrhea

2. Biguanides –> D/N, bloating, flatulence, lactic acidosis, anorexia

Question 7

Which medications can cause weight gain?

Answer 7

1. Sulfonylureas
2. Meglitinides
3. D-phenylalanine

Question 8

Rapid acting insulin info.

Answer 8

Onset: 5-15 mins
Peak: 30-90 mins
Duration: 4-6 hours

Question 9

Short acting (regular) insulin

Answer 9

Onset: 30-60 mins
Peak: 2-3 hours
Duration: 5-8 hours

Question 10

Intermediate/NPH

Answer 10

Onset: 2-4 hours
Peaks: 4-10 hours
Duration: 10-16 hours

Question 11

Long-acting insulin: Lantus

Answer 11

Onset: 2-4 hours
Peaks: NONE
Duration: 20-24 hours

Question 12

Long-acting insulin: Levemir

Answer 12

Onset 3-8 hours
Peaks: NONE
Duration: 5.7-23.2 hours

Question 13

Side effects: Alpha-glucosidase Inhibitor

Answer 13

Flatuence, diarrhea

Question 14

Side effects: Biguanides

Answer 14

Diarrhea, nausea, bloating, anorexia, flatulence, lactic acidosis

Question 15

Side effects: Meglitinides

Answer 15

hypoglycemia, wt gain, upset stomach

Question 16

Side effects: Sulfonylurea

Answer 16

hypoglycemia, Wt gain

Question 17

Side effects: Thiazolidinediones

Answer 17

anemia, birth control will not work well, bladder cancer

Question 18

Side effects: D-phenylalanine

Answer 18

Hypoglycemia, wt gain

Question 19

Side effects: GLP-1 Analogs

Answer 19

nausea, headaches, hypoglycemia

Question 20

Which medications cause GI issues?

Answer 20

Biguanides, AGIs, GLP-1 analogs, Meglitinides

Question 21

What 4 things does Incretin Mimetics do?

Answer 21

1. Increases production of insulin
2. Decreases glucose produced by the liver
3. Decreases gastric emptying
4. Decreases appetite which can help people lose wt

Question 22

What does metformin do?

Answer 22

1. Decrease glucose produced by the liver
2. Increases insulin sensitivity
3. Decrease absorption of CHO you consume

Question 23

Helps to decrease the amount of glucose made by the liver:

Answer 23

1. Amylin mimetic
2. Biguanide
3. DPP-4 inhibitors
4. Thiazolidinediones
5. GLP-1 receptor agonists
6. Insulin

Question 24

Helps your pancreas to make more insulin (secretion):

Answer 24

1. DPP-4 Inhibtors
2. Meglitinides
3. Sulfonylureas
4. GLP-1 receptor agonists

Question 25

Helps to improve the way that insulin works in your muscles (sensitivity):

Answer 25

1. Biguanides

2. Thiazolidinediones

Question 26

Helps to slow down the break down of starches/of food in your stomach and intestine:

Answer 26

Alpha-glucosidase inhibitor/Amylin mimetics and GLP-1 receptor agonists