Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology-UMFLINT Winter 2023 > Diabetes drugs > Flashcards

Diabetes drugs Flashcards

1
Q

Sulfonylureas

A

promote insulin release, hypoglycemia risk, impaired B-cell production, cardiovascular toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Glipizide

A

sulfonylurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Glyburide

A

sulfonylurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Glimepiride

A

sulfonylurea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Detemir

A

long acting insulin
decreases A1c
gradual release all day long
sticks together lightly for slow release
lower risk of hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Aspart

A

rapid acting insulin
decreases A1c
molecules separate quickly
leave SubQ space faster

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Lispro

A

rapid acting insulin
decreases A1c
molecules separate quickly
leave SubQ faster

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Glargine

A

long acting insulin
decreases A1c
gradual release all day long
sticks together lightly for slow release
lower risk of hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Degludec

A

long acting insulin
decreases A1c
gradual release all day long
sticks together lightly for slow release
lower risk of hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Metformin

A

glucophage
decreases hepatic glucose production
decreases intestinal glucose absorption
sensitizes target cells to insulin
Side effects: lactic acidosis, B12 deficiency, diarrhea, anorexia, dyspepsia
Interaction: cimetidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

SGLT2 Inhibitor

A

increases urinary excretion of glucose (decreasing A1c)
w. loss, decrease BP
Side effects: hypotension, UTI, renal dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dapagliflozin

A

SGLT2 inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Empagilflozin

A

SGLT2 inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Incretin

A

simulates insulin release when eating
decreases risk for hypoglycemia
loss of appetite (w. loss)
doesn’t burn out pancreas
decrease glucagon, increase insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

GLP1 Analogs

A

more potent incretin
NAUSEA and VOMITING**
can cause acute pancreatitis and thyroid c-cell tumors
slow gastric emptying (can cause drug absorption issues)
“-glutide” drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Liraglutide

A

GLP1 Analog

17
Q

Dulaglutide

A

GLP1 Analog

18
Q

Semaglutide

A

GLP1 Analog

19
Q

DPP-IV Inhibitors

A

PO
less potent than GLP1 Analog
well tolerated
low risk of hypoglycemia, GI adverse effects, pancreatitis

20
Q

Sitagliptin

A

DPP-IV inhibitor

21
Q

Thiazolidinediones (TZDs)

A

decreases insulin resistance
can cause: fluid retention, edema, weight gain
Side effects: myocardial infarction, CV death, bladder cancer

22
Q
A

Pharmacology-UMFLINT Winter 2023 (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions