Diabetes Definitions Flashcards
Diabetes mellitus
A metabolic disorder that affects how the body uses sugar (glucose)
Type 1 diabetes mellitus
An autoimmune disease that originates when cells that make insulin are destroyed by the immune system
Type 2 diabetes mellitus
A chronic condition that occurs when the body becomes resistant to insulin or when the pancreas fails to produce enough insulin
insulin
Peptide hormone produced by the beta cells of the pancreatic islets
Exogenous insulin
Insulin that comes from outside the body
Endogenous insulin
Insulin that the pancreas makes to regulate blood sugar levels
Insulin resistance
Pathological condition in which cells either fail to respond normally to the hormone insulin or downregulate insulin receptors in response to hyperinsulinemia
Insulin insufficiency
Your body makes insulin but not the amount that you need
Hypoglycemia
Low blood sugar, levels less than 70 mg/dl
Hyperglycemia
High blood sugar, levels greater than 200 mg/dl
Lipohypertrophy
Is a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin
Glycolysis
Process through which glucose is broken down into water and carbon dioxide with the release of energy
Glycogenolysis
Refers to the breakdown of glycogen to glucose
Gluconeogenesis
Process of producing glucose from non-carbohydrate sources (protein and fat)
Glucagon
Hormone that triggers liver glucagon to convert back to glucose and use for energy
Glucose
Sugar in blood stream
Glycogen
Is the stored form of glucose (energy)
Polyuria
Excessive urine
Polyphagia
Excessive hunger/eating
Polydipsia
Intense thirst
Microvascular
Relating to the smallest blood vessels
macrovascular
Relating to the larger blood vessels
Retinopathy
Disease of the retina which results in impairment or loss of vision
Nephropathy
Damage to the small blood vessels in the glomeruli of the kidney
Neuropathy
Disease or dysfunction of one or more peripheral nerves, typically causing numbness or weakness
Cerebrovascular
Disease of the blood vessels supplying the brain
cardiovascular
Disease of the blood vessels supplying the heart
Basal-Bolus insulin therapy
Exogenous insulin therapy that mimics physiological insulin secretion of a “normal” pancreas
Basal insulin
Long acting insulin that covers the blood glucose the liver makes naturally, 24 hrs a day
Bolus insulin
Fast acting insulin that is given for the rise in blood glucose that occurs when food is consumed
Correction insulin
Fast acting insulin that is given in addition to scheduled insulins to bring an elevated blood glucose back into target range
Onset
Duration of time it takes for a drugs effect to come to prominence upon administration
Peak
Time period when the effect of the drug is at optimal strength
Duration
Length of time that the drug is effective