Diabetes Flashcards
Which DM med works in the gut and inhibits the absorption of carbs from the brush border of the intestines?
Alpha Glucosidase Inhibitors
What medications are indicated for children (>10yo) with diabetes?
Metformin and insulin
Which DM Med must you skip a dose if you skip a meal and add a dose if you add a meal?
Meglitinides
Which DM Med is most at risk for hypoglycemia?
Sulfonylureas
How long must you hold Metformin when having iodinated contrast?
Day of and 48 hours after
Which DM Med has a black box warning against use with CHF?
TZDs
Which DM drug class can cause hypotension?
SGLT2 inhibitors (due to volume loss)
Sulfonylureas cannot be used in patients that have a cross-sensitivity to what two drug classes?
Sulfonamides or thiazides diuretics
Acute pancreatitis is a contraindication for which DM Med?
GLP-1
It’s normal to have glucose in urine with which DM Med?
SGLT2 inhibitors
Which DM Med interacts with oral contraceptive pills and will need backup?
TZDs
Which DM drug class has compliance issues due to increased flatulence?
Alpha Glucosidase Inhibitors
Which drug class is contraindicated for bladder cancer?
TZDs
Which DM Med is well tolerated in the elderly?
DPP-4s
Which DM Med can also improve lipid profile?
Metformin (Biguanide)
Which DM Med can increase TG levels
Actose (a TZD)
What are the diagnostic criteria for diabetes? HbA1C >= \_\_\_\_ FPG >= \_\_\_\_ OGTT >= \_\_\_\_ Random plasma glucose >= \_\_\_\_
HbA1C >= 6.5%
FPG >= 126 mg/dL
OGTT >= 200 mg/dL
Random plasma glucose >= 200 mg/dL
Gestational diabetes is caused by what?
Placental hormones.
-They have an anti-insulin effect and increase glucose resistance
History of pancreatitis is contraindicated for which DM Med?
DPP-4 inhibitors
What is the HbA1C goal drug therapy for DM according to ADA?
<7%
Which two antihypertensives can Diabetic patients take?
ACE or ARB because they are renal protective
Lactic acidosis is a rare complication of which DM Med?
Metformin
The two DM meds that cause weight gain are ______ and _______.
TZDs and Sulfonylureas
What abx can cause hypoglycemia?
Sulfonamides and tetracyclines
