Diabetes Flashcards
Pre-Diabetes Impaired Fasting Plasma Glucose (IFPG)
or equal to 100 mg/dL on two occasions
Pre-diabetes Impaired Glucose Tolerance
2hr plasma glucose level is 140-199mg/dL
Two Prophylactic Medications for Diabetes:
ACE Inhibitors and Statins
DX Type I: Fasting Plasma Glucose (FPG)
> or= 126mg/dL
DX Type I: 2hr plasma glucose
> or= 200mg/dL using a glucose load
DX Type I: A1c
> or=6.5%
ABC’s of Diabetes
A1c, Blood Pressure, and Cholesterol
S/Sx of DKA:
Dehydration, Anorexia/Vomiting, Kussmaul Respirations, Blood Sugar >300mg/dL, Arterial pH <7.3, Ketones in blood/urine
TX of DKA:
Electrolyte replacement, 0.9 or 0.45% Norm. Saline, IV raid acting insulin (only mix Regular with saline), Assess: LOC, I&O’s, FSBS, Blood/urine ketones, Cardiac and Resp.
Characteristics of Metabolic Syndrome:
Insulin resistance, elevated insulin levels, decreased HDL’s, Increased LDL’s, Increased triglycerides, hypertension.
Glucotrol
Sulfonylureas
DiaBeta
Sulfonylureas
Sulfonylureas
Increase insulin production from pancreas; drug of choice; allergy alert of sulfa drugs
Metformin
Meglitinides
Glucophage
Meglitinides
Meglitinides
Reduces glucose production by the liver and increases insulin sensitivity at the tissue level. Increases transport of glucose into the cells; used in the prevention of type 2
Precose
Alpha-Glucosidase
Glycet
Alpha-Glucosidase
Alpha-Glucosidase
(starch Blockers) slows down the absorption of CHO in the small intesitines. Improves post-prandial glucose levels
Actos
Thiazolidiones
Avandia
Thiazolidiones
Thiazolidiones
Insulin sensitizers; most effective with people who have insulin resistance
Januvia
Dipeptidyl Peptidase-4 Inhibitors
Dipeptidyl Peptidase-4 Inhibitors
Increases incretin causing insulin release; major benefit: Absence of wt gain as SE
Symlin
Decreases rate food moves through the stomach so blood sugar rises slower, lowers the amount of glucose produced in the liver, triggers feeling full (T1/T2)
Byetta
Incretin mimetic increasing the amount of insulin released (T2 only)
Hypoglycemia occurs when blood glucose is:
Less than 70mg/dL
S/Sx of hypoglycemia
confusion, irritability, diaphoresis, tremors, hunger, weakness–> unconsciousness/death
The Somogy Effect:
A rebound effect in which an overdose of insulin induces hypoglycemia. Usually occuring during the hours of sleep, the somogy effect produces a decline in blood glucose level in response to too much insulin
The Dawn Phenomenon
Is characterized by hyperglycemia that is present on awakening in he morning resulting from the release of conterregulatory hormones in the predawn hours.
Autonomic neuropathy can affect:
nearly all body systems and lead to hypoglycemic unawareness, bowel incontinence and diarrhea, and urinary retention.