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farmacos grupos y nombres > diabetes > Flashcards

diabetes Flashcards

1
Q

Metformina accion

A

activacion de AMPK inhibiendo complejo 1 cadena respiratoria

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2
Q

biguadinas

A

metformina

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3
Q

metformina RAM

A

Diarrea y molestias
Acidosis lacticas
Deficit de B12 y acido fólico

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4
Q

sulfunilureas

A

Glibenclamida
Glipizida

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5
Q

sulfunourea o glibenclamida accion

A

inhibicion canala K/ATP de celula pancreatica, ingreso de calcio y secrecion de insulina

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6
Q

Glibenclamida RAM

A

Hipoglicemia
aumento de peso

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7
Q

contraindicaicon Metformina

A

VFG <30
Enfermedad hepática
hipoxemia crónica

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8
Q

contraindicacion Sulfunoureas o glibenclamida

A

VFG < 45
Insuficiencia hepática

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9
Q

inhibidor de DPP4

A

sitagliptina
Saxagliptina

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10
Q

accion de DPP4

A

prolonga vida media de GLP1, inhibe DPP4 dando efecto incretina

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11
Q

RAM de saxagliptina o Semaglutide

A

Vomitos y nauseas

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11
Q

Contrindicacion IDPP4

A

Cancer de tiroides
Pancreatitis

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12
Q

contraindicacion de GLP1

A

Cancer de tiroides
VFG<30

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13
Q

GLP1 nombres

A

semaglutide
Liraglutide

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14
Q

Accion de semaglutide

A

agonista receptor GLP1

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15
Q

efecto de GLP1 y DPP4

A

estimula secrecion de insulina, inhiben secrecion de glucagon y disminuye vaciamiento gástrico

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16
Q

iSGLT2

A

empaglifozina
Dapaglifozina
Pioglifozina

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17
Q

empaglifozina accion

A

inhibe reabsorciond e glucosa de TCP y aumenta excrecion de glucosa en la orina y sodio

18
Q

RAM de dapaglifozina

A

itu
Deshidratacion
Cetoacidosis

19
Q

activadores PPARy

A

pioglitazona
Rosiglitazona

20
Q

RAM de pioglitazona

A

aumento de peso
edema
Empeora IC
Riesgo de fracturas óseas

20
Q

accion de rosiglitazona

A

ligando sisntético de PPARy captando acidos grasos y aumenta sensibilidad a la insulina y suprime acciond e glucagon

21
Q

inhibidores de a glucosidasa

A

acarbosa

21
Q

accion de acarbosa

A

inhibe la a glucosidasa, y genera menor absorciond e carbohidratos

22
Q

RAM de inhibidor de a glucosidasa

A

Dolor abdominal
diarrea
obstruccion intestinal

23
Q

insulina en higado
sisntesis de acidos gracos
glucogeno
gluconeogenesis

A

+ sisntesis de acidos gracos
+ glucogeno
- gluconeogenesis

24
Q

insulina en tejido adiposo
Sintesis de acidos grasos
lipolisis

A

+ sisntesis de acidos grasos
- lipolisis

25
Q

musculo inuslina
sisntesis de glucógeno
Glut 4

A

+ sisntesis de glucógeno
+ Glut 4

26
Q

RAM insulinas

A

hipoglicemias
lipodistrófia (inyeccion )

27
Q

insulina basal
humana
intermedia

A

Intermedia NPH

28
Q

NPH

A

Humulin
insuman N
Insulatard

29
Q

peak de Humulin

A

8 - 12 hrs

30
Q

admininstracion de Humulin o inuman N

A

ayuno o antes de acostarse

31
Q

prolongada basal

A

Detemir
Glargina 100

32
Q

peak de glargina 100 y detemir

A

no tiene peak

33
Q

administracion de detemir o glargina 100

A

1 - 2 veces día

34
Q

cristalina

A

rápida humana

34
Q

cristalina

A

humulin Actrapid
HM insuman

35
Q

administracion cristalina

A

30 min antes de comer

36
Q

peak de humalin Actrapid

A

2- 3 hrs

37
Q

´rapida analoga

A

insulina Aspartica
lispro
Glusina

38
Q

administracion lispro o aspártica

A

15 min antes de comer

38
Q

peak lispro o aspártica

A

30 a 90 min

farmacos grupos y nombres (5 decks)

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