diabetes

Question 1

Metformina accion

Answer 1

activacion de AMPK inhibiendo complejo 1 cadena respiratoria

Question 2

biguadinas

Answer 2

metformina

Question 3

metformina RAM

Answer 3

Diarrea y molestias
Acidosis lacticas
Deficit de B12 y acido fólico

Question 4

sulfunilureas

Answer 4

Glibenclamida
Glipizida

Question 5

sulfunourea o glibenclamida accion

Answer 5

inhibicion canala K/ATP de celula pancreatica, ingreso de calcio y secrecion de insulina

Question 6

Glibenclamida RAM

Answer 6

Hipoglicemia
aumento de peso

Question 7

contraindicaicon Metformina

Answer 7

VFG <30
Enfermedad hepática
hipoxemia crónica

Question 8

contraindicacion Sulfunoureas o glibenclamida

Answer 8

VFG < 45
Insuficiencia hepática

Question 9

inhibidor de DPP4

Answer 9

sitagliptina
Saxagliptina

Question 10

accion de DPP4

Answer 10

prolonga vida media de GLP1, inhibe DPP4 dando efecto incretina

Question 11

RAM de saxagliptina o Semaglutide

Answer 11

Vomitos y nauseas

Question 11

Contrindicacion IDPP4

Answer 11

Cancer de tiroides
Pancreatitis

Question 12

contraindicacion de GLP1

Answer 12

Cancer de tiroides
VFG<30

Question 13

GLP1 nombres

Answer 13

semaglutide
Liraglutide

Question 14

Accion de semaglutide

Answer 14

agonista receptor GLP1

Question 15

efecto de GLP1 y DPP4

Answer 15

estimula secrecion de insulina, inhiben secrecion de glucagon y disminuye vaciamiento gástrico

Question 16

iSGLT2

Answer 16

empaglifozina
Dapaglifozina
Pioglifozina

Question 17

empaglifozina accion

Answer 17

inhibe reabsorciond e glucosa de TCP y aumenta excrecion de glucosa en la orina y sodio

Question 18

RAM de dapaglifozina

Answer 18

itu
Deshidratacion
Cetoacidosis

Question 19

activadores PPARy

Answer 19

pioglitazona
Rosiglitazona

Question 20

RAM de pioglitazona

Answer 20

aumento de peso
edema
Empeora IC
Riesgo de fracturas óseas

Question 20

accion de rosiglitazona

Answer 20

ligando sisntético de PPARy captando acidos grasos y aumenta sensibilidad a la insulina y suprime acciond e glucagon

Question 21

inhibidores de a glucosidasa

Answer 21

acarbosa

Question 21

accion de acarbosa

Answer 21

inhibe la a glucosidasa, y genera menor absorciond e carbohidratos

Question 22

RAM de inhibidor de a glucosidasa

Answer 22

Dolor abdominal diarrea obstruccion intestinal

Question 23

insulina en higado sisntesis de acidos gracos glucogeno gluconeogenesis

Answer 23

+ sisntesis de acidos gracos + glucogeno - gluconeogenesis

Question 24

insulina en tejido adiposo Sintesis de acidos grasos lipolisis

Answer 24

+ sisntesis de acidos grasos - lipolisis

Question 25

musculo inuslina sisntesis de glucógeno Glut 4

Answer 25

+ sisntesis de glucógeno + Glut 4

Question 26

RAM insulinas

Answer 26

hipoglicemias lipodistrófia (inyeccion )

Question 27

insulina basal humana intermedia

Answer 27

Intermedia NPH

Question 28

NPH

Answer 28

Humulin insuman N Insulatard

Question 29

peak de Humulin

Answer 29

8 - 12 hrs

Question 30

admininstracion de Humulin o inuman N

Answer 30

ayuno o antes de acostarse

Question 31

prolongada basal

Answer 31

Detemir Glargina 100

Question 32

peak de glargina 100 y detemir

Answer 32

no tiene peak

Question 33

administracion de detemir o glargina 100

Answer 33

1 - 2 veces día

Question 34

cristalina

Answer 34

rápida humana

Question 34

cristalina

Answer 34

humulin Actrapid HM insuman

Question 35

administracion cristalina

Answer 35

30 min antes de comer

Question 36

peak de humalin Actrapid

Answer 36

2- 3 hrs

Question 37

´rapida analoga

Answer 37

insulina Aspartica lispro Glusina

Question 38

administracion lispro o aspártica

Answer 38

15 min antes de comer

Question 38

peak lispro o aspártica

Answer 38

30 a 90 min