Diabetes Flashcards
Diagnostic Tests for diabetes?
In order to determine whether or not a patient has pre-diabetes or diabetes, health care providers conduct a:
- Fasting Plasma Glucose Test (FPG)
- Oral Glucose Tolerance Test (OGTT)
- HgA1C
Either test can be used to diagnose pre-diabetes or diabetes.
What are the criteria for a diagnosis of diabetes mellitus
- 126 and higher for Fasting Plasma Glucose
- 200 and higher for Oral Glucose Tolerance Test
- 6.5% and higher for HgA1C
Define Fasting.
Fasting is defined as no caloric intake for at least 8 hours.
How should the Oral Glucose Tolerance Test be performed?
- Two-hour plasma glucose
- The test should be performed using a glucose load containing the equivalent of 75g glucose.
Classic symptoms of diabetes?
- polyuria, polydipsia, polyphagia, and unexplained weight loss
- hyperglycemic crisis, a random plasma glucose greater than 200 mg/dL
- random is defined as any time of day without regard to time since last meal
Diabetes diagnostic test special note?
Each test must be confirmed on a subsequent day, under similar circumstances
When is repeat testing unwarranted?
If a patient is seen with a hyperglycemic crisis or clear symptoms of hyperglycemia with a random plasma glucose greater than or equal to 200 mg/dL, repeat testing is not warranted.
Hypoglycemia treatment?
- Recommended treatment of hypoglycemia is the immediate oral administration of a rapidly absorbed form of glucose, which can be repeated as necessary.
- For people who are unconscious or unable to swallow, glucagon may be given intramuscularly or subcutaneously, to raise blood glucose through hepatic glycogenolysis.
What is Diabetic Ketoacidosis? (DKA)
- DKA most commonly occurs in a person with type 1 diabetes
- Hyperglycemia- Glucose levels are severely elevated.
- Lack of insulin leads to increased release of fatty acids from adipose tissue- ketoacidosis
What is Hyperosmolar Hyperglycemic State? (HHS)
- HHS occurs frequently in people with type 2 diabetes.
- Hyperglycemia- Glucose levels are severely elevated.
- Hyperosmolarity with dehydration
- Absence of ketoacidosis
Diabetes manifestations (3 P’s)?
- Polyuria
- Polydipsia
- Polyphagia
What is Polyuria?
- Polyuria (frequent and excessive urination) occurs as a result of osmotic diuresis caused by excess glucose in the urine
- As a result of diuresis, sodium, chloride, and potassium are excreted in the urine, and water loss is severe.
What is Polydipsia?
After polyuria, dehydration results and polydipsia (excessive thirst) occurs.
What is Polyphagia?
- Because cells receive no glucose, cell starvation triggers polyphagia (excessive eating).
- Despite eating vast amounts of food, the person remains in starvation until insulin is available to move glucose into the cells.
What happens with insulin deficiency?
- With insulin deficiency, fats break down, releasing fatty acids.
- Conversion of fatty acids to ketone bodies (small acids) provides a backup energy source resulting in ketosis
- Weight loss occurs