Diabetes Flashcards
The body’s preferred, primary energy source for cellular metabolism
Glucose
What are the functions of the Pancreas
Exocrine and Endocrine function: Somatostatin - regulates release of insulin and glucagon
What is the function of Insulin
Stimulates cellular absorption of glucose.
- transport glucose into cells
- turns glucose into fats
- promotes transport of glucose to liver
What is the function of Glucagon
Released during Hypoglycemia
Promotes conversion of glycogen into glucose: Raises blood sugar level
Type of DM that occurs when the immune system attacks the insulin-producing beta cells in the pancreas
Type 1 DM
Insulin resistance even though insulin present
AND Altered response to glucose
Results
Hyperglycemia
Onset: Adult (seen in obese children)
Gradual increase of resistance to insulin
Type 2 DM
What are the extrinsic risk factors of Type 2 DM?
obesity
sedentary lifestyle
diet
What are the intrinsic risk factors of Type 2 DM
Ethnicity: African-American, Asian, Pacific Islander, Latin
Males >45yo
HTN, Hyperlipidemia
Family history of DM
What are the treatments involved with Type 2 DM?
Medication: Oral and insulin injection
Nutritional Counseling
Stress management
Exercise
What are the delivery devices for insulin?
Insulin syringe
Insulin pen
Insulin pump
Jet injector
What are the effects of Stress Cortisol Release?
increases visceral obesity, low grade inflammation, leptin, and insulin resistance.
What benefits does exercise have on Type 2 DM?
Increases -beta-cell mass -insulin -insulin sensitivity -glucose uptake -glucose and fatty acid oxidation Decreases -glucagon -blood glucose -hemoglobin A1c -fat mass -hepatic glucose production
What is Gestational Diabetes?
Developed during pregnancy Causes Weight gain Genetic predisposition Resistance to insulin 2° hormone changes Low HDL, elevated triglycerides MAY be more likely to develop Type 2 DM later in life
Where is glycogen stored?
The Liver
T/F: During periods of hypoglycemia, glucagon is released by the pancreas.
True
What are the Big 3 Signs and Symptoms of DM?
Polydipsia (thirst) Polyuria (urination) Polyphagia (hunger) *also... Hyperglycemia Hyperglycosuria (high excretion of glucose in urine) Weight loss Increased appetite Nausea Blurred vision Amenorrhea (absence of menstrual period) ED