Dexamethasone

Question 1

Presentation

Answer 1

8mg in 2ml glass vial

Question 2

Pharmacology

Answer 2

A corticosteroid secreted by the adrenal Cortex.
Actions: relieves inflammatory reactions
Provides immunosuppression

Question 3

Metabolism

Answer 3

By the liver and other tissues; excreted predominantly by the kidneys

Question 4

Indications

Answer 4

1. Bronchospasm associated with acute respiratory distress not responsive to nebulised salbutamol
2. Moderate-severe croup
3. Acute exacerbation of COPD
4. Adult stridor (nob-foreign body obstruction)

Question 5

Contraindications

Answer 5

Known hypersensitivity

Question 6

Precautions

Answer 6

Solutions which are not clear or are contaminated should be discarded

Question 7

Route of administration

Answer 7

IV administered over 1-3 mins, oral

Question 8

Side effects

Answer 8

Nil of significance

Question 9

Special notes

Answer 9

Does not contain an anti microbial agent, therefore use solution immediately and discard any residue.
Iv effects:
Onset 30-60mins
Peak 2 hours
Duration 36-72 hours