Devo Lect 17 - Endoderm Flashcards
Main tissues from endoderm
Digestive tube (gut, liver, gall bladder, pancreas), respiratory tube (trachea, bronchi, lungs)
Pharyngeal Arches
Form early (stage 14, 30 days), 4 pairs; found in all vertebrates
Structures from pharyngeal ouches
Inside the arches, lined with endoderm cells, become 1: auditory tube and tympanic cavity; 2: tonsils; 3: Parathyroid and thymus; 4. Thyroid and parathyroid.
Cartilages formed from pharyngeal pouches
- Meckel’s cartilage (jaw), malleus and incus; 2. Stapes, styloid process; 3. Hyoid bone; 4. Thyroid and cricoid cartilage and tracheal rings
Changes in digestive tube
Cells become specialized - gastric glands, intestinal cells (microvilli); due to endoderm-mesoderm interactions
Liver development
Hepatic diverticulum buds from the foregut as foregut develops; mesenchyme cells induce endoderm cells to proliferate;
Stage 23
About two months; end of embryogenesis, all organs are formed. After this it is called a fetus
Respiratory tube development
induction from mesenchyme cells around it; buds from the pharynx, then branches; laryngotracheal endoderm - lining of trachea, bronchi, alveoli - different types of cells (due to GFs); lungs one of last organs to fully develop
Fetal respiration
Diaphragm becomes functional in last trimester, begins to contract, fetus inhales small amounts of amniotic fluid; helps passages of lungs to expand and expand, not collapse;
Premature babies and respiration
Lungs contain water early on, which will cause the lungs to collapse; development of surfactant in the lungs comes around 6 months; surfactant is made of lipids which disperse the water; if born before then they baby might have trouble breathing