Development of Urinary System Flashcards
What is the embryonic origin of the kidneys?
Intermediate mesoderm
What is the first part of the kidney to develop and in which region?
The pronephros Cervical region
What is in a nephrotome?
Glomerulus, Bowman’s capsule, proximal and distal convoluted tubule, collecting duct
What is the importance of the pronephros?
Produces a pronephric DUCT which extends from the cervical region to the cloaca Drives development of the next developmental stage
What is the cloaca?
Common chamber for the hindgut and urinary systems. Anterior - forms the urogenital sinus Posterior - forms the anus
What are the three key things that develop in urinary embryology?
Pronephros Mesonephros Metanephros
What happens during regression of the pronephric system?
Mesonephric tubules develop which will later form the Bowman’s capsule Capillaries develop which later form the glomerulus
What makes up a renal corpuscle?
Glomerulus and Bowman’s capsule
What is the urogenital ridge?
Area of intermediate mesoderm which gives rise to embryonic kidney and the gonad.
What induces the development of the definitive kidney?
The ureteric bud which sprouts from the mesonephric duct
What does the mesonephros do during development?
Performs renal function in the embryonic kidney
How does the collecting system develop?
Ureteric bud makes contact with the metanephric tissue so that it expands and branches to form the renal pelvis - splits into major and minor calyces
Where are the collecting system and excretory components derived from?
Collecting system - ureteric bud Excretory component - intermediate mesoderm under influence of ureteric bud
Where does the metanephric kidney appear?
In the caudal region
Describe the ascent of the metanephric kidney
In the pelvis, metanephros receives arterial supply from a pelvic branch of the aorta During its ascent, it is vascularised by arteries that come from the aorta at continuously higher levels. Lower vessels usually degenerate.