development of tooth and its supporting tissues Flashcards
at what day of development the primary epithelial band develops?
37 days of development
what does the primary epithelial band does?
it gives rise to two subdivisions that ingrow into the ectomesenchyme which are the dental lamina and vestibule lamina.
what are the three stages of tooth development?
cap stage, bud stage and bell stage
important growth factor/ genes names of oral epithelium ?
BMP ( bone morphogenic protein) SHH ( sonic hedgehog) FGF (fibroblast growth factor ) WNT ( wigless related integration) TNF ( tumorous necrosis factor )
genes of ectomesenchyme?
BMP ( Bome morphogenic protein
ACTIVIN
what does the vestibule lamina makes?
the vestibule
what is the bud stage?
the first epithelial incursion into the ectomesenchymec ells
what happens in the cap stage of development ?
at this stage u can see the formative tissues of the tooth which are the enamel organ ( the cap part) dental papilla dental follicle lateral
the rudimentary things in cap stage are ?
enamel cord
enamel niche
enamel knot
what does enamel knot makes?
cusp tip of the teeth
tell the formation of stellate reticulum ?
the cells of the enamel organ have abundant glycosaminoglycans in the extracellular compartment between the epithelial cells
the glycosaminoglycans are hydrophilic and attarct water which increase the volume of extracellular compartment of enamel organ, the cells are forced apart but are still intact through the desmosomes and thus are star shaped and called stellate reticulum.
what happens at bell stage?
by the start of this stage shape of the tooth has already been decided
the cells bordering the dental lamina are columnar and makes up the inner enamel epithelium
the point at which the inner and outer enamel epithelium meet at the rim of the enamel organ is called
zone of reflection
what makes the stratum intermediate ?
the cells between inner enamel epithelium and stellate reticulum differentiate to make the stratum intermediate.
the two other important things happening in the bell stage are?
the dental lamina joins the tooth germ to 4.the oral epithelium fragments eventually separating the tooth from the oral epithelium
and then the inner enamel epithelium completes its folding to allow us to recognize the shape of the future crown