development of tooth and its supporting tissues Flashcards

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1
Q

at what day of development the primary epithelial band develops?

A

37 days of development

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2
Q

what does the primary epithelial band does?

A

it gives rise to two subdivisions that ingrow into the ectomesenchyme which are the dental lamina and vestibule lamina.

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3
Q

what are the three stages of tooth development?

A

cap stage, bud stage and bell stage

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4
Q

important growth factor/ genes names of oral epithelium ?

A
BMP ( bone morphogenic protein) 
SHH ( sonic hedgehog) 
FGF (fibroblast growth factor ) 
WNT ( wigless related integration) 
TNF ( tumorous necrosis factor )
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5
Q

genes of ectomesenchyme?

A

BMP ( Bome morphogenic protein

ACTIVIN

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6
Q

what does the vestibule lamina makes?

A

the vestibule

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7
Q

what is the bud stage?

A

the first epithelial incursion into the ectomesenchymec ells

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8
Q

what happens in the cap stage of development ?

A
at this stage u can see the formative tissues of the tooth which are 
the enamel organ ( the cap part) 
dental papilla 
dental follicle 
lateral
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9
Q

the rudimentary things in cap stage are ?

A

enamel cord
enamel niche
enamel knot

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10
Q

what does enamel knot makes?

A

cusp tip of the teeth

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11
Q

tell the formation of stellate reticulum ?

A

the cells of the enamel organ have abundant glycosaminoglycans in the extracellular compartment between the epithelial cells
the glycosaminoglycans are hydrophilic and attarct water which increase the volume of extracellular compartment of enamel organ, the cells are forced apart but are still intact through the desmosomes and thus are star shaped and called stellate reticulum.

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12
Q

what happens at bell stage?

A

by the start of this stage shape of the tooth has already been decided
the cells bordering the dental lamina are columnar and makes up the inner enamel epithelium

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13
Q

the point at which the inner and outer enamel epithelium meet at the rim of the enamel organ is called

A

zone of reflection

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14
Q

what makes the stratum intermediate ?

A

the cells between inner enamel epithelium and stellate reticulum differentiate to make the stratum intermediate.

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15
Q

the two other important things happening in the bell stage are?

A

the dental lamina joins the tooth germ to 4.the oral epithelium fragments eventually separating the tooth from the oral epithelium
and then the inner enamel epithelium completes its folding to allow us to recognize the shape of the future crown

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16
Q

the fragments of dental lamina (series/ seres ) that presist can cause what diseases in the tooth?

A
  1. eruption cyst
  2. delay eruption
  3. odontome
  4. supernumeray teeth
17
Q

first the dentin and enamel deposits where?

A

the cusp tip of the teeth

18
Q

from what part the permanent teeth are made

A

dental lamina

19
Q

how are the molars made?

A

the dental lamina extends posteriorly into the ectomesenchyme into the oral epithelium, this backwards extension makes epithelium outgrowths that associated with ectomesenchyme makes the first second and third molars

20
Q

the entire primary dentition is initiated between?

A

6-8 weeks

21
Q

permnanent teeth are made between?

A

20 in utero and 10 months after birth

22
Q

the permanent molars?

A

20 in utero and 5 years (third molar)

23
Q

what is the origin of tooth germ?

A

ectoderm (ectomesenchyme)

24
Q

the tooth germ makes up the?

A
  1. dental papilla
  2. enamel organ
  3. dental follicle
25
Q

what type of cells the dental papilla makes up?

A

odontoblast

undifferntiated mesenchymal fibroblast

26
Q

what does the enamel organ makes up?

A
  1. cervical loop
  2. outer enamel epithelium
  3. stellate reticulum
  4. startum intermedium
  5. inner enamel epithelium
27
Q

what cells the dental follicle makes up?

A
  1. cementoblast
  2. fibroblast
  3. osteoblast
28
Q

cervical loop makes up what?

A

HERS hertwigs rooth sheath

29
Q

inner enamel epithelium makes up?

A

ameloblasts

30
Q

hers make up?

A

root form