DEVELOPMENT OF THE FACE AND PALATINE Flashcards
when does the development of the face occur
between 4th and 8th week
during the 4th week, there are facial prominence
true
frontonasal prominence
Frontonasal prominence – formed by the proliferation of mesenchymal neural crest cells ventral to the forebrain
mandibular and maxillary prominences
Mandibular and maxillary prominences – parts of the 1st pharyngeal arch.
Space lies between the maxillary prominences, covered by the oropharyngeal membrane; this is known as the stomatodeum, the precursor to the mouth and pituitary gland
nasal placode
depression of the ectoderm due to induction by the ventral portion of the brain
on the 5th week
nasal pits are formed
Nasal development is instigated by the appearance of raised bumps called nasal placodes on both sides of the frontonasal prominence. These then invaginate to form nasal pits, with medial and lateral nasal prominences on either side.
after nasal prominence are formed frontonasal prominence becomes
frontal process
during the 7th week of development
maxillary prominence continues to grow/increase in size, compressing medial nasal prominence towards each other in the midline to form 1 median nasal prominence
upper lip
2 maxillary prominence and median nasal prominence
medial nasal prominence forms
- Philtrum, primary palate, upper 4 incisors, and associated jaw,
- bridge of the nose, median septum, columellar, frenulum inside the lip
maxillary prominence form
cheeks and maxilla
the nose is formed from 5 prominence
- frontanasalis= bridge of the nose
- Mp= crest and the tip of the nose
- lateral nasal p= sides of the nose
nasolacrimal groove separates
Mp and the lateral nasal prominence
ectoderm in the nasolacrimal groove
will form epithelium cord of cells which will later form nasolacrimal duct and after this, Mp and LNP merges
the upper part of the nasolacrimal duct will dilate to form
lacrimal sac which opens up to the inferior meatus of nasal
cavity
Mp will form a triangular mass of mesenchyme behind the philtrum of the lip called
palatal process/primary palate
Mp will give rise to two palatine shelf which is projected vertically on the side of the tongue and will later
elevate to lie horizontal to the tongue where they fuse
as the palate shelf fuses, they will merge with the
the median palatine process to form the definitive palatine process
fusion of the two palatal shelves is facilitated by
a sticky substance is known as glycocelics present on the epithelium of palatal shelves
facial clefts
Cleft lip Incomplete cleft lip Unilateral cleft lip Bilateral cleft lip Cleft palate Median cleft lip Oblique facial clefts
Frontonasal
Forehead, bridge of nose, medial and lateral nasal prominences
Medial nasal
Philtrum, primary palate, upper 4 incisors, and associated jaw
Lateral nasal
Sides of the nose
Maxillary (1st pharyngeal arch)
Cheeks, lateral upper lip, secondary palate, lateral upper jaw
Mandibular (1st pharyngeal arch)
Lower lip and jaw