Development Of Orofacial Structures Flashcards

1
Q

Neurocranium

A

Derived from mesenchyme
-cartilaginous and membranous components

Bones of skull that house brain
-frontal, parietal, temporal, and occipital

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2
Q

Viscerocranium

A

Derived from mesenchyme
-cartilaginous and membranous components

Facial bones
-maxillary, Mandibular, nasal, lacrimal, etc

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3
Q

Neurocranium-Cartilaginous Parts

A

Occipital bone,
body of sphenoid bone,
ethmoid, and petrous and mastoid parts of temporal

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4
Q

Neurocranium-Membranous parts

A

Frontal and parietal bones

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5
Q

Viscerocranium-Cartillagenous

A

NCCs give rise to bones and connective tissues

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6
Q

Viscerocranium-Membranous

A

Maxillary prominence
Squamous part of temporal bone
Maxila
Zygomatic bone

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7
Q

What bones come from PA1

A

Malleus (connected to tympanic membrane) and Incus

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8
Q

What bones arise from PA2?

A

Stapes, Styloid process of temporal, and lesser horn

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9
Q

What bones arise from PA3?

A

Greater Cornu of hyoid b

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10
Q

What bones arise from PA4?

A

-GOTCHA!

Just laryngeal cartilage

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11
Q

What is Scaphocelpaly?

A

Immature closure of Sagittal suture
-causes wedge shaped head
—long and narrow

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12
Q

What is brachycephaly?

A

Immature closure of whole coronal suture

-tall head; tower like

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13
Q

Plagiocephaly-Cause?

A

Half of coronal suture

-twisted shaped head, one side sticks out

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14
Q

Trigionocephaly-Cause?

A

Frontal suture

-rounded point on forehead

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15
Q

5 facial primordial

A
  • 2 maxillary prominences
  • 2 Mandibular prominences
  • 1 frontal
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16
Q

When do the facial primordial appear?

A

Appear during week 4

-around the stomodeum

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17
Q

What separates stomodeum from primordial pharynx?

A

The oropharyngeal membrane

-ruptures around day 26

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18
Q

What are the first parts of the face to form?

A

Oropharyngeal membrane ruptures, and then the mandibular prominences come together

When the don’t.. BUTT CHIN
-or called a chin dimple

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19
Q

Maxillary Prominences

A

Give rise to upper lip, maxilla, and secondary palate

-grow medially

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20
Q

Frontonasal prominence

A

Surrounds ventrolateral part of brain

-forehead and nose

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21
Q

Nasal Placodes

A

Bilateral oval thickenings of surface ectoderm

-gives rise to medial and lateral nasal prominences

22
Q

What do medial and lateral nasal prominences form?

A

Nasal pits.. which then form primordial nares

23
Q

What does the median nasal prominence form?

A

Grows toward midline w growth of maxillary prominences

-forms philtrum

24
Q

Lateral nasal prominence formation

A

Separated from maxillary prominence by nasolacrimal groove

-merges w it by week 6

25
Nasal Cavity formation
Nasal placodes depress and form nasal pits -mesenchyme from medial and lateral nasal prominences induce pits to become deeper=sacs Sacs grow dorsal and ventral until they rupture at end of week 6 to form oral nasal cavity
26
Primordial Choanae
Connection between nasopharynx and nasal cavity
27
In Parkinson’s disease, what is the first thing to go?
Sense of smell as much as 10 years before
28
Weeks of palatogenesis
Weeks 6-12, with critical weeks 6-9
29
Primary Palate Formation
Primary -fusion of medial nasal prominence forms medial palatine process -premaxillary part separated by incessive fossa
30
Secondary Palate Formation
Develops from Lateral Palatine Process | -Mesenchymal projections extending from internal aspects of maxillary prominences
31
Final Palate Formation
Bone extends from maxillae and palatine bones into lateral palatine process to form hard palate -posterior does not ossify
32
Nasal Septum
Downward growth of internal parts of merged medial nasal prominences -fuses with lateral palatine processes
33
Cleft Lip and Palate-Most Common
Unilateral cleft lip on left is most common -Risk factors include genetic and environment —SHH, TGF-a
34
Choanal Atresia
Abnormalities of pterygoid plates and midfacial growth abnormalities
35
What does choanal atresia present as?
Airway obstruction, noisy breathing, or cyanosis that worsens during breathing but improves with crying
36
Tongue Development-Anterior 2/3
Median swelling ingulfed by lateral swelling -PA1 mesenchyme CN VII taste, IX sensation
37
Pharyngeal Part of Tongue
Hypopharyngeal eminences (arch 4) overgrows copula (arch 2)
38
Anterior 2/3 of tongue innervation
Sensation -V3-lingual Taste -CN VII-Facial Motor -CN XII
39
Posterior 1/3 of tongue Innervation
Mucosa/Taste -CN IX Muscles -CN XII Sensation to Pharynx -CN X Palatoglossus M -CN X
40
Glossoschissis
Split tongue
41
Ankyloglossia
Short lingual frenulum | -problem when breast feeding and speaking
42
Macroglossia
Enlarged tongue seen in Downs Syndrome
43
Odontogenesis
Induced from NCC and Oral Epithelium -Dental Lamina lays down first, then tooth buds form from this —made of ectoderm
44
Tooth Bud Contents
Enamel organ -enamel epithelium and inner enamel epithelium Dental Papilla -dentin and pulp Dentil Follicle -mesenchym surrounding dental papilla and enamel organ —cementum
45
Where do odontoblasts come from?
From dental papilla, next to inner enamel epithelium
46
Where do ameloblasts come from and what do they do?
From inner enamel epithelium differentiating | -produce enamel
47
Epithelial Root Sheeth
Fusion of inner and outer enamel epithelium | -root dentin produced by odontoblasts
48
Pulp
Central dental papilla
49
Cementum
inner cells of dental sac from cementoblasts
50
Periodontal ligament
Outer cells of dental sac
51
Eruption of teeth
Deciduous root of teeth reabsorbed by osteoclasts, deciduous teeth fall out and adult teeth arise