Development Of Orofacial Structures Flashcards

1
Q

Neurocranium

A

Derived from mesenchyme
-cartilaginous and membranous components

Bones of skull that house brain
-frontal, parietal, temporal, and occipital

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2
Q

Viscerocranium

A

Derived from mesenchyme
-cartilaginous and membranous components

Facial bones
-maxillary, Mandibular, nasal, lacrimal, etc

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3
Q

Neurocranium-Cartilaginous Parts

A

Occipital bone,
body of sphenoid bone,
ethmoid, and petrous and mastoid parts of temporal

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4
Q

Neurocranium-Membranous parts

A

Frontal and parietal bones

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5
Q

Viscerocranium-Cartillagenous

A

NCCs give rise to bones and connective tissues

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6
Q

Viscerocranium-Membranous

A

Maxillary prominence
Squamous part of temporal bone
Maxila
Zygomatic bone

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7
Q

What bones come from PA1

A

Malleus (connected to tympanic membrane) and Incus

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8
Q

What bones arise from PA2?

A

Stapes, Styloid process of temporal, and lesser horn

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9
Q

What bones arise from PA3?

A

Greater Cornu of hyoid b

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10
Q

What bones arise from PA4?

A

-GOTCHA!

Just laryngeal cartilage

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11
Q

What is Scaphocelpaly?

A

Immature closure of Sagittal suture
-causes wedge shaped head
—long and narrow

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12
Q

What is brachycephaly?

A

Immature closure of whole coronal suture

-tall head; tower like

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13
Q

Plagiocephaly-Cause?

A

Half of coronal suture

-twisted shaped head, one side sticks out

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14
Q

Trigionocephaly-Cause?

A

Frontal suture

-rounded point on forehead

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15
Q

5 facial primordial

A
  • 2 maxillary prominences
  • 2 Mandibular prominences
  • 1 frontal
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16
Q

When do the facial primordial appear?

A

Appear during week 4

-around the stomodeum

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17
Q

What separates stomodeum from primordial pharynx?

A

The oropharyngeal membrane

-ruptures around day 26

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18
Q

What are the first parts of the face to form?

A

Oropharyngeal membrane ruptures, and then the mandibular prominences come together

When the don’t.. BUTT CHIN
-or called a chin dimple

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19
Q

Maxillary Prominences

A

Give rise to upper lip, maxilla, and secondary palate

-grow medially

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20
Q

Frontonasal prominence

A

Surrounds ventrolateral part of brain

-forehead and nose

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21
Q

Nasal Placodes

A

Bilateral oval thickenings of surface ectoderm

-gives rise to medial and lateral nasal prominences

22
Q

What do medial and lateral nasal prominences form?

A

Nasal pits.. which then form primordial nares

23
Q

What does the median nasal prominence form?

A

Grows toward midline w growth of maxillary prominences

-forms philtrum

24
Q

Lateral nasal prominence formation

A

Separated from maxillary prominence by nasolacrimal groove

-merges w it by week 6

25
Q

Nasal Cavity formation

A

Nasal placodes depress and form nasal pits
-mesenchyme from medial and lateral nasal prominences induce pits to become deeper=sacs

Sacs grow dorsal and ventral until they rupture at end of week 6 to form oral nasal cavity

26
Q

Primordial Choanae

A

Connection between nasopharynx and nasal cavity

27
Q

In Parkinson’s disease, what is the first thing to go?

A

Sense of smell as much as 10 years before

28
Q

Weeks of palatogenesis

A

Weeks 6-12, with critical weeks 6-9

29
Q

Primary Palate Formation

A

Primary
-fusion of medial nasal prominence forms medial palatine process

-premaxillary part separated by incessive fossa

30
Q

Secondary Palate Formation

A

Develops from Lateral Palatine Process

-Mesenchymal projections extending from internal aspects of maxillary prominences

31
Q

Final Palate Formation

A

Bone extends from maxillae and palatine bones into lateral palatine process to form hard palate
-posterior does not ossify

32
Q

Nasal Septum

A

Downward growth of internal parts of merged medial nasal prominences
-fuses with lateral palatine processes

33
Q

Cleft Lip and Palate-Most Common

A

Unilateral cleft lip on left is most common

-Risk factors include genetic and environment
—SHH, TGF-a

34
Q

Choanal Atresia

A

Abnormalities of pterygoid plates and midfacial growth abnormalities

35
Q

What does choanal atresia present as?

A

Airway obstruction, noisy breathing, or cyanosis that worsens during breathing but improves with crying

36
Q

Tongue Development-Anterior 2/3

A

Median swelling ingulfed by lateral swelling
-PA1 mesenchyme

CN VII taste, IX sensation

37
Q

Pharyngeal Part of Tongue

A

Hypopharyngeal eminences (arch 4) overgrows copula (arch 2)

38
Q

Anterior 2/3 of tongue innervation

A

Sensation
-V3-lingual

Taste
-CN VII-Facial

Motor
-CN XII

39
Q

Posterior 1/3 of tongue Innervation

A

Mucosa/Taste
-CN IX

Muscles
-CN XII

Sensation to Pharynx
-CN X

Palatoglossus M
-CN X

40
Q

Glossoschissis

A

Split tongue

41
Q

Ankyloglossia

A

Short lingual frenulum

-problem when breast feeding and speaking

42
Q

Macroglossia

A

Enlarged tongue seen in Downs Syndrome

43
Q

Odontogenesis

A

Induced from NCC and Oral Epithelium

-Dental Lamina lays down first, then tooth buds form from this
—made of ectoderm

44
Q

Tooth Bud Contents

A

Enamel organ
-enamel epithelium and inner enamel epithelium

Dental Papilla
-dentin and pulp

Dentil Follicle
-mesenchym surrounding dental papilla and enamel organ
—cementum

45
Q

Where do odontoblasts come from?

A

From dental papilla, next to inner enamel epithelium

46
Q

Where do ameloblasts come from and what do they do?

A

From inner enamel epithelium differentiating

-produce enamel

47
Q

Epithelial Root Sheeth

A

Fusion of inner and outer enamel epithelium

-root dentin produced by odontoblasts

48
Q

Pulp

A

Central dental papilla

49
Q

Cementum

A

inner cells of dental sac from cementoblasts

50
Q

Periodontal ligament

A

Outer cells of dental sac

51
Q

Eruption of teeth

A

Deciduous root of teeth reabsorbed by osteoclasts, deciduous teeth fall out and adult teeth arise