Development of NS

Question 1

what txn factors need to be expressed in the dorsal roof plate?

Answer 1

pax 3 and pax 7 and BMP 4 (TGF-B)

Question 2

what txn factors need to be in the floor plate

Answer 2

Shh and pax 6

Question 3

what is a ependymal cell?

Answer 3

glial cell that stays in the ventricular zone

Question 4

what are the zones in developing CNS

Answer 4

ventricular, mantle, marginal

Question 5

where does spinal cord end in adults and where does tap go

Answer 5

ends: L2-L3

spinal tap L4-L5

Question 6

what ganglia are sensory

Answer 6

dorsal root ganglia

Question 7

CNS white matter =

Answer 7

tracts

Question 8

CNS gray matter =

Answer 8

nuclei

Question 9

PNS cell bodies

Answer 9

ganglia

Question 10

tracts in the PNS

Answer 10

nerves

Question 11

where do ventral efferents live

Answer 11

intermediate lateral grey matter leaves ventral root
T1-L2
S2-S4

Question 12

Somatic system CNS

Answer 12

1 nerve in and 1 nerve out

Question 13

Rhizotomy

Answer 13

nerves separated then identified via electrical stimulation
sensory nerves in spinal cord can be cut,
some nerves that lead too to much muscle tone which is a condition of cerebral palsy and spacticity are then cut
-good for chronic pain

Question 14

congenital insensititiy to pain

Answer 14

person cannot feel pain

• SCN9A sodium channel found in DRG
• sensation of pain in periphery is lost and not sent to dorsal root

Question 15

autonomic system

Answer 15

1 nerve in and 2 nerves out

pregang, and post gang axon