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Volatile Anesthetic Agents > Desflurane > Flashcards

Desflurane Flashcards

1
Q

Desflurane Pulmonary effects

A
  • respiratory similar to enflurane and slightly less than isoflurane
  • extrememly noxious pulmonary irritant
  • not recommended for inhalation induction and probably a poor choice for patients with reactive airway disease
  • respiratory depressant
  • very slight tachypnea
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2
Q

Desflurane Physical Property: boiling point

A

23.5 C

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3
Q

Desflurane Physical Property:SVP

A

669.2 mmHg

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4
Q

Desflurane Physical Property: MAC

A

6%

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5
Q

Desflurane Physical Property: Blood/Gas Coefficient

A

0.42

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6
Q

Desflurane Physical Property: Brain/Blood coefficient

A

1.3

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7
Q

Desflurane Physical Property: Muscle/blood coefficient

A

2

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8
Q

Desflurane Physical Property: Fat/Blood coefficient

A

27

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9
Q

Desflurane Cardiovascular Effects: autonomic reflexes blcoke

A

causes more myocardial depression and arterial vasodilation as iso

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10
Q

Desflurane Cardiovascular Effects: autonomic reflexes left in tact

A

less myocardial depression and arterial vasodilation and greater tachycardia than iso

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11
Q

Desflurane Cardiovascular Effects: autonomic tone

A

important in the CV responses of des

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12
Q

Desflurane Cardiovascular Effects: BP

A

abrupt increase in des increase BP 30 mmHg increases HR 30 bpm, doubles SNS activity, increases plasma epinephrine

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13
Q

Desflurane Cardiovascular Effects: MI

A

evidence of no MI ischemia in patient receiving des compared to iso or sufentanil

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14
Q

Desflurane Cardiovascular Effects: Beware

A

tachycardia greatly impacts coronary blood flow causing possible ischemia

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15
Q

Desflurane Neuro Effects: MEPs

A

does not affect

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16
Q

des hepatic metabolism

A

0.02%

17
Q

des and hepatic artery

A

preserves hepatic artery flow better than halothane and maintains hepatic oxygen supply better than halothane

Volatile Anesthetic Agents (8 decks)

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