Dermatology Flashcards

1
Q

What is basal cell carcinoma?

A

a type of cancer that begins in the basal cells

  • basal cells produce new skin cells as old ones die
  • limiting sun exposure can help prevent these cells from becoming cancerous
  • typically appears as a white waxy lump or a brown scaly patch, raised pearly and rolled borders, telangiectasis, central ulcer on sun-exposed areas, such as the face and neck
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the treatment for basal cell carcinoma?

A

prescription creams fluorouracil (FU)) and imiquimod, photodynamic therapy (PDT), and surgical excision with clear margins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the body percentages for burns?

A
  • rule of 9’s: head 9%, each arm 9%, chest 9%, abdomen 9%, each anterior leg 9%, each posterior leg 9%, upper back 9%, lower back 9%, genitals 1%
  • palmar method: patient’s palm equated to 1%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is a 1st degree burn?

A

sunburn

-erythema of involved tissue, skin blanches with pressure, the skin may be tender

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is a 2nd degree burn?

A

partial thickness

-skin is red and blistered, skin is very tender

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is a 3rd degree burn?

A

full thickness

-burned skin is tough and leathery, skin non-tender

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is a 4th degree burn?

A

into the bone and muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the treatment for burns?

A

monitor ABCs, fluid replacement, sulfadiazine
-children with >10% total body surface area and adults with >15% total body surface ares burns need formal fluid resuscitation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is cellulitis?

A

an acute bacterial skin and skin structure infection of the dermis and subcutaneous tissue; characterized by pain, erythema, warmth, and swelling
-margins are flat and not well demarcated
-caused by staphylococcus and streptococcus in adults
H. influenzas or strep pneumonia in children

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the tx for cellulitis?

A
  • treat mild cellulitis (MSSA) with cephalexin or dicloxacilin
  • treat methicillin-resistant staphylococcus aureus infection (MRSA) with
  • trimethoprim-sulfamethoxazole (TMP-SMZ) 1 DS tab PO BID
  • clindamycin 300-450 mg PO
  • doxycycline 100 mg PO BID
  • Intravenous vancomycin or linezoild
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the signs and symptoms of mastitis/breast abscess?

A

nipple discharge, redness, warm skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the signs and symptoms of breast cancer?

A

nipple discharge, breast discomfort, breast mass

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the signs and symptoms of gynecomastia?

A

nipple discharge, breast enlargement, overweight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the signs and symptoms of inflammatory breast cancer?

A

nipple discharge, breast enlargement, redness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the signs and symptoms of hypogonadism?

A

nipple discharge, sexual dysfunction, reduced sex drive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are GU processes that cause discharge?

A
  • infections of the vagina, such as a yeast infection, bacterial vaginosis, trichomoniasis, human papillomavirus (HPV), or herpes
  • Infection of the cervix (cervicitis)
  • an object in the vagina, such as a forgotten tampon
  • sexually transmitted infections (STIs), such as chlamydia or gonorrhea
  • various sex practices, such as oral-to-vaginal and anal-to-vaginal contact
  • vaginal medicines or douching
  • menopause: vaginal discharge, an absence of menstruation, anxiety
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the signs and symptoms of abscess?

A

pain, redness, with or without discharge

18
Q

What is a drug eruption?

A

drug-induced exanthema are the most common cutaneous reactions to drugs, responsible for approximately 90 percent of all drug rashes
-the most commonly prescribed medications (eg, antibiotics, sulfonamides) are implicated in most cases

19
Q

What is the dx of drug eruption?

A

clinical evaluation and skin biopsy - shows necrotic epithelium

  • diagnosis is often obvious from the appearance of lesions and rapid progression of symptoms
  • histologic examination of sloughed skin shows necrotic epithelium, a distinguishing feature
  • differential diagnosis in SJS and early TEN include erythema multiforme, viral exanthema, and other drug rashes
20
Q

What is the tx for drug eruption?

A

stop all potentially offending medications

  • early admission to burn out or pediatric intensive care unit for initial stabilization and management of fluid, electrolytes, and nutrition; airway stability; and eye care
  • prompt ophthalmology and dermatology consultation
  • Intravenous immunoglobulin (IVIG)
  • steroids used to be the treatment of choice are now thought to be an increased risk for sepsis
21
Q

What is melanoma?

A

usually a pigmented lesions with an irregular border, irregular surface, or irregular coloration
-melanoma occurs when the pigment-producing cells that give color to the skin (melanocytes) become cancerous

22
Q

What are the symptoms of melanoma?

A
  • symptoms might include a new, unusual growth or a change in an existing mole
  • melanomas can occur anywhere on the body
  • asymmetrical, unevenly pigmented patch/plaque with a nodule and an irregular border
23
Q

What are the ABCDE of melanoma?

A
Asymmetry 
Border is irregular 
Color variability (blue, red, white) 
Diameter (increase or > 6 mm) 
Elevation (raised) 
-prognosis of melanoma is most strongly associated with the depth of the lesion, based on the Clark Classification System of Microstaging
24
Q

What is the clark classification system of Microstaging?

A
  • level I: confined to the epidermis (in situ)
  • level II: invasion into the papillary dermis
  • level III: penetration to the papillary-reticular dermis
  • level IV: invasion into the reticular dermis
  • level V: penetration into the subcutaneous fat
25
Q

What is the tx for melanoma?

A

may involved Mohs surgery, radiation, medications, or in some cases chemotherapy

26
Q

Where do pressure ulcers most often affect?

A

serum and hip most often affected, reposition every 2 hours

27
Q

What is a stage I pressure ulcer?

A

erythema of localized area, usually non-blanching over the bony surface

28
Q

What is a stage 2 pressure ulcer?

A

partial loss of dermal layer, resulting in pink ulceration

29
Q

What is a stage 3 pressure ulcer?

A

full dermal loss often exposing subcutaneous tissue and fat

30
Q

What is a stage 4 pressure ulcer?

A

full thickness ulceration exposing bone, tendon, or muscle

-osteomyelitis may be presetn

31
Q

How is a stage 1 pressure ulcer treated?

A

aggressive preventive measures, thin film dressings for protection

32
Q

How is a stage 2 pressure ulcer treated?

A

occlusive dressing to maintain healing, transparent films, hydrocolloids

33
Q

How is a stage 3-4 pressure ulcer treated?

A

debridement of necrotic tissue

  • exudative ulcers will benefits from absorptive dressings such as calcium alginates, foams, hydrofibers
  • dry ulcers require occlusive dressing to maintain moisture, including hydrocolloids, and hydrogels
34
Q

What are the differential diagnosis for a rash?

A
  • Antibiotics side effects: adverse antibiotic reactions may occasionally mimic infection by causing fever, skin rashes, and mental status changes
  • Zinc deficiency is characterized by a perioral pustular rash
  • Paget disease is a rare condition characterized by an intraepithelial adenocarcinoma of the perianal skin. The most common presenting complaint is intolerable pruritus and examination typically revels a well-demarcated, erythematous, eczematous rash
  • Herpes zoster presents with classic vesicular lesions which develop unilaterally in a dermatomal distribution
  • Herpes simplex presents with clear vesicles on an erythematous base; crusting
  • Systemic rheumatoid disease (still’s disease) usually presents with multiple (more than five) involved joints, fever, lymphadenopathy, hepatosplenomegaly, rash, subcutaneous nodules, and pericarditis
  • Fat emboli from long bone fractures cause a syndrome characterized by respiratory insufficiency, coagulopathy, encephalopathy, and an upper body petechial rash
35
Q

What is the tx for a rash?

A

decide whether to observe and treat empirically, perform diagnostic testing, or refer to dermatology for workup

36
Q

What is redness/erythema?

A

can be caused by infection (cellulitis), massage, electrical treatment, acne medication, allergies, exercise, solar radiation (sunburn), photosensitization, cutaneous radiation syndrome, mercury toxicity, blister agents, niacin administration, or waxing and tweezing of the hairs - any of which can cause the capillaries to dilate, resulting in redness
-erythema is a common side effect of radiotherapy treatment due to patient exposure to ionizing radiation

37
Q

What are the differential diagnosis for redness/erythema?

A
  • ulcer
  • eczema
  • stasis and contact dermatitis
  • drug allergy
  • cellulitis, MRSA
  • erysipelas
  • chemical burns
  • angioedema and urticaria
  • venous insufficiency
  • Impetigo
  • herpes zoster
  • scarlet fever
  • tinea infections
  • psoriasis
  • acne
  • polycythemia vera
  • paronychia
  • osteomyelitis
  • abscess
  • autonomic hyperreflexia
  • lymphadenitis
  • carbuncle
  • neutropenia
38
Q

What is squamous cell carcinoma?

A

raised, slightly pigmented skin lesion; ulceration/exudate; chronic scab; itching

39
Q

What is urticaria?

A

(hives) is a skin rash triggered by a reaction to certain foods, medications, stress, or other irritants
- symptoms include blanch able, pruritic, raised, red, or skin-colored papules, wheels or plaques on the skin’s surface
- (+) Darier’s sign: localized urticaria appearing where the skin is rubbed (histamine release)
- angioedema: painless, deeper form of urticaria affecting the lips, tongue, eyelids hand, and genital

40
Q

What is the tx for urticaria?

A

hives usually go away without treatment, but antihistamine medications are often helpful in improving symptoms

  • If anaphylaxis give epinephrine 0.3 -0.5 mg; use 1:1,000 dilution for IM route and 1:10,000 for IV route
  • peds: epinephrine 0.1 mg/kg SC/IV