Dermatology

Question 1

What are the most likely causative agents with respect to erythema multiforme?

Answer 1

• HSV infection is most common etiology
• Mycoplasma pneumoniae has also been implicated
• HSV labialis (and, less commonly, HSV genitalis), is implicated in 60-70% of episodes of EM and are believed to trigger nearly all episodes of recurrent EM
• Frequently in association with sun exposure
• Drug related EM is less common (<10% of patients)
  May be associated with NSAIDs, acetaminophen, sulfonamides, antibiotics

Question 2

What condition is most likely to be associated with intensely pruritic pleomorphic lesions over the extensor surfaces of elbows, knees, shoulders and scalp/forehead?

Answer 2

Celiac Disease - Dermatitis herpetiformis