Dermatology

Question 1

What type of dermatological condition has this histology

Answer 1

Wart

Question 2

What type of dermatological condition has this histology

Answer 2

Psoriasis

Question 3

What type of dermatological condition has this histology

Answer 3

Rash

Question 4

Couldn’t be bothered cropping lol

Answer 4

Pemphigus and pemphigoid

Question 5

What type of skin is this?

Answer 5

Palmar skin

Question 6

Label the following diagram

Answer 6

A: Nail Plate

B: Lanula

C: Nail root

D: Cuticle

E: Nail matrix

F: Nail bed
G: Hyponychium

H: Free edge of nail

Question 7

What are signs of acute intermittent porphyria?

Answer 7

Abdo pain, pain on urination, psychaitric signs, fast pulse and a high BP

Question 8

Build up of what occurs in porphyria cutanea tarda and what enzyme defiency causes this

Answer 8

Build up of uroporphinogen III due to uroporphinogen decarboxylase deficiency

Question 9

What could be a cause for a child crying when in direct sunlight? What build up and what enzyme deficiency?

Answer 9

Protoporphyria (build-up of protoporphyrin 9 due to ferrochelatase deficiency)

Question 10

What causes acute intermittent porphyria

Answer 10

Build up of porphobilinogen due to deficiency of porphobilinogen deaminase

Question 11

What are symptoms of porphyria cutanea tarda?

Answer 11

Onycholysis (nail detachment), blistering of sun exposed skin, hyperpigmentation, hypertrichosis

Question 12

What are symptoms of erythropoetic protoporphyria

Answer 12

Painful photsensitivity with a burning/itching sensation

Question 13

First line treatment of rosacea

Answer 13

Topical metronidazole

Question 14

First line treatment for acne vulgaris

Answer 14

Benzyl peroxide or topical clindamycin??

Question 15

What is epidermolysis bullosa?

Answer 15

Inherited breakdown of anchoring between epidermis and dermis

Question 16

What genetic defect causes epidermyolysis?

Answer 16

Simplex: AD KRT5 and KRT14 gene issues

Junctional: AR laminin and collagen issue

Dystrophic caused by AD or reciessive COL7A1 gene issue

Question 17

Describe psoriasis presentation

Answer 17

Red, flaky, crusty plaques of skin covered ith silvery scales normally on elbows, knees, scalp and lower back. Can be itchy and painful. Usually develops in under 35s

Question 18

Treatment of psoriasis

Answer 18

Topical corticosteroid or vitamin D3 analogue as first line

Or coal tar/keratolytic

Question 19

What are three causes of neurogenic pruitis

Answer 19

CNS receptors effect due to thyroid disease or malignancy

Question 20

How to diagnose pemphigus/pemphigoid

Answer 20

Biopsy with immunofluorescence

Question 21

Describe toxic epidermyl necrolysis

Answer 21

A severe acute superficial desquamating eruption often secondary to drugs e.g. antibiotics and presents with fever, malaise, painful erosions and generalised erythema

Question 22

Do creams cause more contact sensitisation that ointments?

Answer 22

Yes because they contain more preservatives

Question 23

What dermatological condition is associated to coeliac

Answer 23

Dermatitis herpetiformis