Dermatology (389-430) Flashcards
flat discoloration
macule
elevated skin lesion
papule
elevated skin lesion >1cm
plaque
small fluid containing lesion
vesicle
pruritic erythematous area that can enlarge to form urticaria
Wheal
Large fluid filled lesion >0.5cm in diameter
Bulla
accentuated skin markings as thick as epidermis as a result of scratching
lichenification
irregular raised lesion from scar tissue hypertrophy
keloid
flat pinhead NON BLANCHING red-purple lesion caused by hemmorhage into skin
petechiae
larger than petechiae
purpura
closed epithelium lined cavity or sac continaing liquid or semi solid material
cyst
increased thickness of the stratum corneum seen in chronic dermatitis
hyperkeratosis
hyperkeratosis with retention of the nuclei in stratum corneum on histopathology and thinning of stratum granulosum (seen in psoriasis)
parakeratosis
loss of cohesion between the epidermal cells (seen in pemphigus vulgaris)
acantholysis
intercellular edema causing strethcing and loss of desmosomal attachment allowing formation of blisters (seen in acute and subacute dermatitis)
spongiosis
Herald patch
pityriasis rosea
What bacterium is often the cause of acne (inflammation of the pilosebaceous unit)
Propionibacterium acnes
open comedones
blackheads
closed comedones
whiteheads
Tx for acne
Retin-A, benxoyl peroxide. If acne is scarring, consider accutane or in females spironolactone
superficial skin infection causing honey crusted lesions esp in children around nose and mouth
Impetigo caused by strep pyogenes or staph aureus
Hot tub folliculitis organism
Pseudomonas aeruginosa
What are the classic signs of inflammation?
rubor (red)
calor (hot)
dolor (pain)
tumor (swelling)
pus collection of one hair follicle often by S. aureus
Furuncle
Pus collection involving many hair follicles
Carbuncle
Cellulitis in which infection remains in the superficial dermal layer leading to edema localized beneth skin
erisypelas (a/w strep, tx with penicillin)
Infection of skin surrounding nail margin, can extend to tendons within hand
Paronychia
Tx with warm compress, I&D if area is purulent, add abx if severe
Infection from skin layers down to fascial planes with severe pain out of proportion, fever, white count. Tx?
Necrotizing faciitis
Tx with immediate surgical debreidment. Tx with ceftriaxone or penicillin
Prognosis of necrotizing fasciitis
increased mortalitiy unless debreidment is rapid
Sunburn with “goosebumps”, strawberry tongue, Patia’s lines (rash in axillae and groin)
Scarlet Fever
plugged apocrine glands presents in inflammed masses in the groin and axilla,
Hiradenitis suppurativa
irregular erythematous rash found along major skin folds, commonly seen in adult diabetics and caused by corynebacterium spp.
Woods lamp shows - coral red flourescense, KOH prep negative
Dx? Tx?
Erythrasma
Tx with erythromycin
silvery white scaling with pink plaques on EXTENSOR SURFACES like elbows and knees and scalp (esp behind ears) Also associated with FINGERNAIL PITTING WITH ONYCHOLYSIS a/w rheumatoid arthritis
psoriasis
What is Auspitz sign?
removal of overlying scale causes pinpoint bleeding –> psoriasis
What is Kobner’s phenomenon
psoriatic lesions appear at sites of cutaenous physical trauma
What type of psoriasis typically presents in child/young adult after streptococcal infection with drop like 1-10mm salmon-pinnk papules with a fine scale?
Guttate psoriasis
What type of psoriasis is often localized to the plams and soles, but can be generalized with pustules
Pustular psoriasis
What type of psoriasis presents with lesions in the interdiginous areas?very erythematous and look amost like candidal or tinea cruris?
Inverse psoriasis