Dermatology 3 Flashcards
Which skin cancer has a worse prognosis?
Squamous cell carcinoma
Which skin cancer is more common?
Basal cell carcinoma
What is the main risk factor for basal cell carcinoma?
UV exposure with skin type 1/2
Describe a classic BCC
Pearly appearance with rolled edge and telangiectasia
Rodent ulcer
DNA mutation in PTCH TSG causes which skin cancer?
Basal cell carcinoma
What is a morphoeic BCC?
Ill-defined borders
Waxy
More aggressive
What surgery is performed for recurring/high risk BCCs?
Mohs micrographic surgery
How are BCCs normally treated?
Excision
What are the main precursors to SCC?
Actinic keratoses (aka solar keratosis) - 10% progress to SCC Bowen's disease
What does an SCC look like?
A non-healing ulcer
Punched out and crusted
How do you treat actinic keratoses?
Topical fluorouracil
What causes moles and freckles?
Benign overgrowth of melanocytes from basal layer of epidermis
When is a mole considered invasive?
If it penetrates the dermis
How do you assess a pigmented lesion?
ABCDE assessment
Asymmetry Border irregularity Colour variation Diameter > 6mm Evolving
Itching + bleeding
Which scale measures skin types?
Fitzpatrick scale
What is a slow growing patch of brown skin (often resembles a freckle)?
Lentigo maligna
What can develop from lentigo maligna?
Lentino maligna melanoma = irregularly shaped brown macule that grows slowly
Where do malignant melanomas most commonly metastasise to?
Lymph nodes Liver Lung Bone Brain
What is the management of acne?
Single / then combo: topical steroid - topical retinoids, benzoyl peroxide, topical abx
PO abx - tetracyclines / erythrmocyin
- For max 3 months
COCP eg dianette
PO isotretanoin in specialist