Dermatology Flashcards
UVA
- phototoxic rxn –> exaggerated sunburn
Skin Regeneration process
- very thin, cells move up they die
- Lipids present on skin
- Epidermis mositure determines pliability
Epidermis
- Dry skin, aging, being a barrier
melanocytes
Suntan, vertigo, melanoma
sebacceaus tissue
acne
Sweat gland
heat related
dermis
hair follicles, sebaceuous and sweat gands, sensations of itch, pain, stinging
Factors that affect drug absorption on the skin
Skin Hydration –> Sweat –> Absorption increases
pH of Drug and vehicle
Thickness of application
Temperature of skin
What is a finger-tip unit?
- One FTU equals the top crease of finger to end of finger
- Covers area of two sides of hand
Erythema
- just redness
Bullae
- Bigger version of blistering
Wheal
- Little Bumps
Papule, pustule, nodule, cyst
Acne
Abscess
- Folliculitis –> hair growing back in (acte phase) redness –> 3-4 days after crusting
Scales, plaque and Patch
Lichenification –> SKin thickens over time to protect itself
Excoriation
- Mechnaical irritation
Ulcer
Hole –> Diabetics foot
Macuole
- Frecke
Papule
- Pimple Like
Xerosis
- Dry Skin
Factors that can cause dry skin
- Excessive bathing/showering
- Low humdiity
Aging
Sun damage
Soaps –> not good for skin
Mechanical rubbing
What conditions would a person have drier skin?
Diabetes
Hypothyroidism
Tx for dry skin
Eczema Grade products –> Unscented, non-allergenic, gentlr/soapless, no colours added
Non-drug tx for Dry Skin
- cut back bathing and showering
- less hot water
Pat dry rather than rub
Apply cream/lotion while still dry
Increase water intake and humidifier –> Not a mjor player
Bath Oils
- Oil and surfactant –> few tablespoons
- Can feel good –> No s/e
Colloidal Oatmeal
Tiny effect, but go for it
Water-holding, slight anti-inflammatory, anti-itch
Moisturizers Effectiveness
Bath oils
Lotions
Creams
Ointments
petroleum
Increase in effect, but user acceptance worse
Ceramide
- Ecezma –> Not useful –> needs to get underneath the skin not on top