Dermatology Flashcards
what is BCC a malignancy of?
basal epidermal keratinocytes
a pearly, flesh coloured papule with rolled edge
Associated telangiectaisa.
Ulcerated
Bleeds from minor trauma
What is the diagnosis?
BCC
- what is SCC a malignancy of?
- What are its premalignant lesions known as?
- What is SCC in situ also known as?
- epidermal keratinocytes
- solar keratosis
- bowen’s disease
Ill defined, dome shaped lesion
rapid growing
ulcerated and bleeds easily
multiple associated actinic solar keratoses on surrounding skin.
What is the diagnosis?
SCC
What is malignant melanoma a malignancy of?
Melanocytes
Mole has grown recently
Borders are now irregular
multiple colours
What is the dx?
Malignant Melanoma
- What is the most common form of Malignant Melanoma?
- What is the most aggressive type of malignant melanoma and why?
- What is used to measure depth of spread of melanoma (i.e. T on TNM staging?
- superficial spreading
- nodular - vertical invasion
- breslow thickness
- Inflammatory lesions of acne vulgaris (3)
2. non-inflammatory lesions of acne vulgaris (2)
- papules, pustules, macules
2. comedomes, pseudocysts
stepwise management of acne vulgaris (4)
- single topical therapy - benzyl peroxide or retinoids
- combination topical therapy - benzyl peroxide/retinoids + clindamycin
- oral antibiotics (tetracyclines or erythromycin if contraindicated)/COCP + topical treatments
- oral isotreinoin
elderly patient
itchy, tense blisters, around flexures
mouth is spared
- what is the diagnosis
- pathophysiology
- management
- bullous pemphygoid
- autoimmune
- refer to derm; oral corticosteroids
- Most common subtype of psoriaisis
2. exacerbating factors (5)
- plaque psoriasis
- trauma
alcohol
drugs - beta blockers, lithium, antimalarials, NSAIDS, ACEi
withdrawal of systemic steroids
steptococcal infection (gluttate psoriasis)
NAME THE SUBTYPE OF PSORIASIS BASED ON THE FOLLOWING CLINICAL FEATURES
- well defined, red, scaly patches affecting extensor surfaces, sacrum and scalp
- shiny, smooth, red, well defined patches localised to skin folds and genitals
- transient psoriatic rash with multiple teardrop lesions
- red, tender, rash followed by the appearance of small pustules, which become bigger. Commonly occurs on palms and soles
- plaque psoriasis
- flexural psoriasis
- gluttate psoriasis
- pustular psoriasis
Management of Psoriasis
a) general conservative measure
b) stepwise topical mangagement
c) first line systemic therapy and what this can be useful for
a) regular emollients to reduce scales and pruritis
b) 1. topical potent corticosteroid + vitamin D analogue OD for up to 4 weeks
2. vitamin D analogue BD for up to 8 weeks
3. potent corticosteroid BD for up to 4 weeks, or coal tar preparation
c) methotrexate - associated joint disease
- What other condition is dermatitis herpetiformis associated with and why?
- how is it managed?
- coeliac disease - IgA deposition in dermis leading to inflammatory response
- management of coeliac disease
Dapsone
Itchy, vesicular skin lesions on extensor surfaces
abdominal pain and bloating, weight loss, steatorrhoea
What is the dx?
Dermatitis Herpeteformis
Child with atopic eczema Rash has come on suddenly painful round, punched out lesions feels unwell
What is the dx?
Eczema herpeticum