dermatitis and eczema trigger Flashcards
predominance of IL13 and IL4 suggest what is occuring
acute inflammation of atopic dermatitis
a presentation of scaly plaques/papules with round erosions and cursts suggests what phase of eczema?
subacute
a presentation of erythema, vesicles, bullae, weeping and crusts suggests what phase of eczema
acute eczema
a presentation of scaling, hyper/hypopigmentation and lichenification suggests what phase of eczema
chronic eczema
intense pruritus is the hallmark for what
atopic dermatitis (eczema)
what are common impetiginization agents
Staph
HSV
coxsackie
vaccinia
hyperlinear palms, keratosis pilaris, and hyperpigmentation are all signs of what
atopic dermatitis
along with periorbital scaly plaques, thinning of lateral eyebrows.
in chronic youll see lichenification, scaling and dyspigmentation
gentle cleansers and low strength steroids are a treatment for what?
what are examples of gentle cleansers
atopic dermatitis and nummular eczema
CeraVe, Cetaphil, Vanicream (fragrance free)
what are hte non-steroidal creams used in atopic dermatitis and who cannot use these.
not reccommended in <2 yrs old
- tacrolimus
- pimecrolimus
- crisaborole
when do we use dupulimab? what is the dose?
systemic treatment of atopic dermatitis. 600mg SC then 300mg SC Q 2 weeks
what is the use of antihistamine in atopic dermatitis? what antihistamines do we use?
tx of pruritus
diphenhydramine, hydroxyzine, cetirizine, loratadine
confined to area, sharply marginated, never spreads
irritant contact dermatitis
a rash with a spreading phenomenon that can even spread beyond infected sites is likely what etiology
allergic contact dermatitis
irritiant contact remains in exposure area and is sharply marginated
this most commonly affects the hands, forearms, upper chest, neck and face
airborne contact dermatitis
what type of testing is used for allergic contact dermatitis?
patch testing (must have clinical correltation)
do NOT use skin prick!!
what are haptens and what do they mediate
cause T cell mediated inflammation seen in allergic contact dermatitis
hydrocortisone and desonide are considered high, medium or low potency?
low
triamcinolone, mometasone and fluocinolone are considered high, medium or low potency?
medium
clobetasol, halobetasol and betamethasone dipropionate cream are considered high, medium or low potency?
high
fluocinonide and desoximetasone cream are considered high, medium or low potency?
high
what is PUVA therapy used for?
contact dermatitis, nonpharmacological treatment
also for dyshidrotic eczema!
ICD, cutaneous candidiasis and miliaria can all cause what?
diaper dermatitis
the use of zinc oxide, petroleum jelly as well as sometimes nystatin, clotrimazole, and econazole is for what diagnosis
diaper dermatitis
nystatin, clotrimazole, and econazole for candidiasis if needed
zinc oxide and petroleum jelly for diaper dermatitis
pruritic, coin shaped, scaly plaques with no hx or Fhx of atopy
nummular eczema
interferon therapy for Hep C and venous stasis are both risks for developement of what diagnosis
nummular eczema
Tacrolimus, pimecrolimus, and crisaborole are all used for hwat
localized atopic dermatitis in patients that are >2 years old.
non steroidal
what are the sebum-rich areas of the body and what diagnosis typically effects these areas
face, scalp, neck, upper chest and back
seborrheic dermatitis
pityrosporum yeast is assocaited with which diagnosis
seborrheic dermatitis
presentation is dry and pruritic with erythema and fine greasy scaling.
what areas can this occur in?
seborrheic dermatitis
can occur in obv the scalp, eyebrows, beard, eyelid (probs cuz eyelashes)
but can also occur in posterior ears, external ear canal, upper chest, nasolabial folds, anogenital areas and intertriginous areas
crazy.
MC in patients with HIV, parkinson’s or a generally immunocomp state
seborrheic dermatitis
frequently co-exists with rosacea and psoriasis
seborrheic dermatitis
1st line is ketoconazole shampoo, but can use tar shapmoo, vanicraem Zbar, prythone zinc and other shampoos
what is this dx and what other treatment options are there
seborrheic dermatitis
can use steroids such as clobetasol solution, betamethasone, and flucinolone scalp oil
can use steroids such as clobetasol solution, betamethasone, and flucinolone scalp oil
seborrheic dermatitis
also use shampoos like ketoconazole(1st line), tar and pyrithone zinc
symptoms include pruritus, a sense of heaviness and edema of the lower extremities
stasis dermatitis
MC on the medial ankle. reddish brown discoloration with weeping, crusting and scaling of the skin. can see loss of hair and hyperpigmentaation
stasis dermatitis
how do you treat stasis dermatitis that is weeping
wet compresses (clean water and burrows). topical steroids like triamcinolone/clobetasol (this is just typical tx)
common predisposing factors for this diagnosis are chronic skin conditions, emotional stress, and habitual scratching (porbs d/t anxiety)
lichen simplex chronicus
tx with emollients, intralesional kenalog injections, and traimcinolone
lichen simplex chornicus
what condition can be caused by mid/high potency steroid use and what is the treatment for this
periooral dermatitis.
- taper down from seroid using low potency steorids!
- topical pimecrolimus 1% (can also use erythromycin, metronidazole, azelaic acid, or clinda)
advise patient that it may flare up prior to getting better
topical pimecrolimus 1% has shown to be beneficial in what diagnosis
perioral dermatitis
Pruritic “tapioca like vesicles” common on the hands that burns, itches and is painful.
typically w hx of AD and MC between 20-40
dyshidrotic eczema
MOA: inhibition of T-lymphocyte activation, which prevents release of cytokines.
what drug is this and what class does it belong to?
pimecrolimus cream or tacrolimus ointment
class: calcineurin inhibitors
BBW: rare lymphoma and skin cancer! (teratogenicity)
calcineurin inhibitors (tacrolimus and pimecrolimus)
CI in children <2y/o and with use of occlusive dressings
calcineurin inhibitors (tacrolimus and pimecrolimus)
MOA: Reduces corneocyte production
used in seborrheic derm and tinea versicolor!
selenium sulfide
CI in Oral/ophthalmic/anal/intravaginal use
selenium sulfide
MOA: reduce cell turnover
Use: seborrheic derm
pyrithione zinc
yayyyyy all done!
