Dermatitis Flashcards

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1
Q

what is hyperkeratosis?

A

increased thickness of the keratin layer

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2
Q

what is parakeratosis?

A

persistence of the nuclei in the keratin layer

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3
Q

what is acanthosis?

A

increased thickness of the epidermis

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4
Q

what is spongiosis?

A

oedema between keratinocytes

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5
Q

what is another name for dermatitis?

A

eczema

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6
Q

what are some possible causes of contact allergic dermatitis?

A

chemicals
topical treatments
nickel
plants

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7
Q

what immune cell is involved in contact allergic dermatitis?

A

T cells

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8
Q

how can substances causing contact allergic dermatitis be identified?

A

patch testing

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9
Q

what causes irritant contact dermatitis?

A

non specific physical irritation of the skin i.e. hand washing

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10
Q

how does atopic eczema present?

A

itch

erythema and scaling

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11
Q

what distribution are the lesions in atopic eczema arranged in?

A

a flexural distribution

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12
Q

what diseases are often found alongside atopic eczema?

A

atopic diseases - asthma, allergic rhinitis, food allergy

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13
Q

what are two chronic changes seen in atopic dermatitis?

A

lichenification

excoriation

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14
Q

what is a possible complication of atopic dermatitis?

A

secondary infection

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15
Q

what is the diagnostic criteria for eczema?

A

itching and 3+:

  • visible flexural rash
  • history of flexural rash
  • history of atopy
  • dry skin
  • onset before 3
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16
Q

what is the most important gene implicated in atopic eczema?

A

filaggrin

17
Q

what is eczema herpeticum?

A

a skin infection caused by HSV

18
Q

describe the appearance of eczema herpeticum

A

monomorphic punched out lesions