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SBL > Derm Pharm Crossword > Flashcards

Derm Pharm Crossword Flashcards

1
Q

oral hedgehog pathway inhibitor that can be used for advanced basal cell carcinoma

A

vismodegib

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2
Q

tetracycline used to treat acne

A

minocycline

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3
Q

prescription synthetic topical antimycotic agent with broad spectrum of activity

A

ciclopirox

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4
Q

aminoglycoside antibiotic of Neosporin with activity against gram-negative bacteria

A

neomycin

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5
Q

topical treatment for lesions due to herpes simplex

A

acyclovir

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6
Q

important component of wound healing

A

debridement

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7
Q

class of antifungal drugs with a wide range of activity

A

imidazoles

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8
Q

unless wounds appear clinically infected

A

antibiotics

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9
Q

blocks the conversion of testosterone to more potent androgen dihydrotestosterone

A

finasteride

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10
Q

K+-sparing diuretic with partial agonist properties at androgen receptors that can make it useful for treating menstrual cycle-linked acne or male pattern baldness in adult women

A

spironolactone

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11
Q

low-pressure implementation of this with normal saline is an important component of healing

A

irrigation

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12
Q

control that is now considered a priority for optimal wound closure

A

glycemic

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13
Q

MAP kinase pathway inhibitor useful for melanoma BRAF V600E mutation

A

vemurafenib

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14
Q

route of administration where pharmacokinetic factors influencing absorption and distribution of drug include region

A

cutaneous

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15
Q

broad-spectrum antimicrobial agent widely used in homes and hospitals due to efficacy on skin and oral mucosa with low irritability

A

chlorhexidine

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16
Q

very old remedy for psoriasis; works but color and smell create a challenge

A

tar

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17
Q

agents such as iodine

A

impede

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18
Q

component of plant defenses against bacteria

A

azeleic acid

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19
Q

class of adrenergic agonists administered topically to treat rosacea or red eyes; oxymetazoline and tetrahydrozyline are among the examples

A

alpha

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20
Q

topical antimicrobial agent commonly used to treat acne; local skin irritant and may bleach hair or clothing

A

benzoyl peroxide

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21
Q

treated surgically when possible with 1-2 cm margins and conventional chemotherapy based on dacarbazine

A

melanoma

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22
Q

drug class that may or may not stop the itch

A

antihistamines

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23
Q

can be an effective treatment for acne in women

A

combination oral contraceptives

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24
Q

among the wound coverings preferred during the granulation and epithelialization phases of wound healing

A

low adherence

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25
Q

radiation that may not cause erythema and sunburn but still does contribute to skin aging and photocarcinogenesis; under strict supervision

A

UVA

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26
Q

chemotherapeutic agent useful for melanoma

A

dacarbazine

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27
Q

region where highest potency glucocorticoids should not be used

A

face

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28
Q

late choice for treating ectoparasites

A

lindane

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29
Q

applied to skin to kill microbes

A

antiseptic

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30
Q

when used to treat thrush

A

nystatin

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31
Q

treatment for actinic keratoses derived from Euphorbia peplus sap

A

ingenolmebutate

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32
Q

organophosphate anticholinesterase insecticide

A

malathion

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33
Q

refers to autoantibody mediated hair loss that is treated with corticosteroids and/or an agent such as DPCP to induce a contact dermatitis with typical hair growth restoration in the healed skin

A

alopecia areata

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34
Q

local anesthetic

A

pramozine

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35
Q

counterirritant that provides sensation of cool by stimulating TRPM8 receptors

A

menthol

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36
Q

topical administration formulations have 7 potency classes with many clinicians using one or more from each so that it is possible to taper down to the lowest dose needed to control inflammation after establishing control

A

glucocorticoids

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37
Q

important for optimal wound healing

A

nutrition

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38
Q

characterizes the topical glucocorticoids that should be applied to face

A

low potency

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39
Q

refers to agents such as glycerin

A

humectants

40
Q

very important component of skin care for health care providers

A

moisturizers

41
Q

common cause of diarrhea due to antibiotic-associated colitis

A

C. difficile

42
Q

peptide antibiotic with efficacy against gram-negative bacteria including pseudomonas

A

polymixin B

43
Q

synthetic insecticide similar to that of chrysanthemums

A

permethrin

44
Q

biologic DMARD directed against IL-17a

A

secukinumab

45
Q

titanium dioxide is an example that could be applied

A

sunshade

46
Q

applied to inanimate objects to kill microbes

A

disinfectant

47
Q

topical retinoid administered for the treatment of acne

A

tretinoin

48
Q

topical antihistamine

A

doxepin

49
Q

example of a body region where topically applied agents would be rapidly absorbed

A

axilla

50
Q

chronic kidney disease

A

pruritis

51
Q

local vasoconstriction due to blood volume deficit

A

oxygenation

52
Q

urea

A

horny substance softener

53
Q

blocking this radiation was only goal of early sunscreens; also used to treat psoriasis

A

UVB

54
Q

most important component of infection control

A

hand hygiene

55
Q

alpha 2 adrenergic agonist used as topical vasoconstrictor to treat rosacea

A

brimonidine

56
Q

very useful

A

gloves

57
Q

form on surfaces

A

biofilms

58
Q

refers to substances in moisturizers that form an oily layer to trap water in the skin/treat dry skin; petrolatum

A

emollients

59
Q

to heal best

A

moist

60
Q

both real and fake are well-documented reservoirs for spreading infections in the clinical environment

A

fingernails

61
Q

delayed hypersensitivity reaction that can be caused by substances such as latex and drugs such as neomycin and bacitracin; sometimes induced as treatment of skin disorder

A

contact dermatitis

62
Q

topical immune response modifier used to treat actinic keratoses and basal or squamous carcinomas; also used to treat genital warts

A

imiquimod

63
Q

benzophenones and dibenzoylmethanes are now widely used in these to protect skin

A

sunscreen

64
Q

antibiotic that works similar to macrolides

A

clindamycin

65
Q

effective topical therapy for actinic keratoses

A

5-fluorouracil

66
Q

topical imidazole used to treat nail fungus

A

efinaconazole

67
Q

effective treatment for acne primarily because of its simple/easy to follow strategy with otherwise standard anti-acne agents

A

Proactiv

68
Q

platelet-derived growth factor that stimulated diabetic ulcer repair

A

becaplermin

69
Q

useful topically for fungal infections such as jock itch and athlete’s foot and systemically for fungal nail infections

A

terbinafine

70
Q

anti-inflammatory agent known since ancient times

A

salicylic acid

71
Q

local anesthetic found in topical treatments to relieve pain

A

lidocaine

72
Q

widely used OTC antifungal agent for topical and vaginal infections

A

clotrimazole

73
Q

mixture of zinc oxide and iron oxide in lotion that cools the skin

A

calamine

74
Q

most difficult infectious agent to destroy

A

prions

75
Q

drug class useful for systemic treatment of acne

A

tetracycline

76
Q

macrolide antibiotic

A

erythromycin

77
Q

biologic agents that target this are among the agents useful for psoriasis

A

TNF alpha

78
Q

potent vasodilator due to hyperpolarization via activation of K+ channels

A

minoxidil

79
Q

orally administered insecticide to treat ectoparasites

A

ivermectin

80
Q

most common handwashing error in clinical setting

A

inadequate time

81
Q

~50% water and 50% oil with an emulsifier

A

creams

82
Q

imidazole antifungal drug applied topically for range of fungal infections

A

ketoconazole

83
Q

prototypical non-steroid androgen antagonist

A

flutamide

84
Q

monoclonal antibody against IL-12 and IL-23

A

ustekinumab

85
Q

retinoid administered orally for treatment of severe acne

A

isotretinoin

86
Q

among the imidazole drugs commonly used to treat vulvovaginal candidiasis

A

miconazole

87
Q

orally administered phosphodiesterase type 4 inhibitor used to treat moderate-to-severe plaque psoriasis

A

apremilast

88
Q

among OTC drugs used to treat jock itch and athlete’s foot; like terbinafine

A

tolnaftate

89
Q

good wound coverings during the debridement phase of healing

A

hydrogels

90
Q

peptide antibiotic with activity against gram-positive organisms and some anaerobes; only applied topically to limit systemic toxicity

A

bacitracin

91
Q

the formation of one of these after drug application to the skin may prolong its half-life enough to permit 1/day dosing

A

reservoir

92
Q

antifungal agent reluctantly used systemically but also has topical effects limited to candida infections

A

amphotericinb

93
Q

comprised of ~20% water and 80% oils

A

ointments

94
Q

inhibitors of this signaling pathway can be used to treat advanced basal cell carcinoma (but usually treated surgically and/or topically)

A

hedgehog

95
Q

counterirritant that stimulates TRPV1 channels to cause sensation of heat

A

capsaicin

SBL (5 decks)

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