Derm Introduction- Midterm Material (653) Flashcards

1
Q

Layers of the skin:

A

epidermis, basement membrane, dermis, adnexa, subcutis

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2
Q

What is contained within the dermis?

A

blood vessels, nerves, arrector pili muscles

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3
Q

What is contained within the adnexa?

A

hairs, glands

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4
Q

The arrector pili muscles are ___ muscle

A

smooth

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5
Q

Layers of the epidermis:

A

stratum corneum, stratum granulosum, stratum spinosum, stratum basale

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6
Q

The normal appearance of the stratum corneum is:

A

anucleate, basket-weave appearance

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7
Q

Parakeratosis:

A

retained nuclei in the stratum corneum

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8
Q

What is contained within the stratum spinosum?

A

microfilaments between cell-cell junctions (desmosomes)

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9
Q

Hair follicles are modified extensions of the __

A

epidermis

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10
Q

At the base of a hair follicle is the __, surrounded by hair matrix, which is NOT __

A

papilla, pluripotent

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11
Q

Hair follicle cycle:

A

anagen (growth), catagen (regression), telogen (rest), exogen (shedding)

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12
Q

The majority of dog and cat hair is in the __ phase

A

telogen

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13
Q

Functions of the skin:

A

barrier, sebum/oil production, thermoregulation, sensation, immune function, vitamin D production

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14
Q

The dermatologic minimum database:

A

cytology, skin scraping, trichogram

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15
Q

Primary lesions:

A

papules, pustules, vesicles, bullae, nodules, plaques

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16
Q

Secondary lesions:

A

crusts, epidermal collarettes, scars, lichenification, hyperpigmentation, calluses, excoriations

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17
Q

Primary OR secondary lesions:

A

erosions, ulcers, draining tracts, macules, patches, alopecia, scale, depigmentation, atrophy

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18
Q

Pustule:

A

intra-epidermal pocket filled with purulent material

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19
Q

Vesicle:

A

intra-epidermal or sub-epidermal pocket filled with serous fluid, < 1cm

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20
Q

Bullae:

A

intra-epidermal or sub-epidermal pocket filled with serous fluid, > 1cm

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21
Q

Pustules, vesicles, and bullae rupture easily, so you are more likely to see lesions like ___ on physical examination

A

crusts, erosions, ulcers

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22
Q

Acantholysis:

A

disruption of the desmosomes between keratinocytes leading to pustule formation

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23
Q

DDX of acantholysis:

A

bacterial folliculitis, pemphigus foliaceus, dermatophytosis (Trichophyton)

24
Q

DDX for vesicles:

A

FMD, vesicular exanthema of swine, pemphigus vulgaris

25
Papule:
raised, rounded lesion, < 1cm (often erythematous)
26
Nodule:
raised, rounded lesion, > 1cm
27
Plaque:
raised, FLAT lesion, > 1cm
28
Papules, Nodules, and Plaques are ___ lesions
space-occupying
29
Lichenification:
thickened skin
30
Lichenification commonly co-occurs with __, but is caused by ___
alopecia and/or hyperpigmentation, chrnoic inflammation/trauma
31
Erosion:
partial loss of the epidermis
32
Ulcer:
complete loss of the epidermis that extends through the basement membrane
33
DDX for erosions and ulcers:
primary = necrosis (vasculitis, ischemia, chemical/physical/biologic injury) secondary = pustule, vesicle, nodule rupture
34
Macule:
flat discoloration, < 1cm
35
Patch:
flat discoloration, > 1cm
36
Hyperpigmentation/Melanosis:
additional pigment in skin
37
Depigmentation/Leukoderma:
pigment loss in skin
38
If you see hyperpigmentation, you should perform a ___
diascopy
39
Diascopy:
blanches = hyperemia no blanching = red blood cells outside of the vasculature- coagulopathy, vasculitis
40
Alopecia:
complete hair loss
41
Hypotrichosis:
thinning of the hair coat
42
Primary causes of alopecia:
folliculitis, endocrine, ischemia, genetics
43
Secondary causes of alopecia:
pruritus, surface trauma, pressure
44
Scale:
flaky, white/tan debris on the surface of the skin (dandruff)
45
Hyperkeratosis:
increased stratum corneum
46
Cytology evaluates for:
microbes, inflammatory cells, neoplastic cells
47
Methods for collecting cytology:
direct impression, tape prep, slurry, swab
48
Direct impression cytology is more sensitive for __, and best for __
cocci, crusts, papules, pustules, epidermal collarettes, moist lesions (PYODERMA)
49
Swab collection for cytology is best for:
ears, interdigital spaces
50
Acetate tape prep for cytology is best for __ areas, and more sensitive for __
dry areas (lichenification, scale- no ulceration or erosion), yeast
51
The slurry technique for cytology has been mainly used for __
horses (dermatophilosis)
52
What is the main drawback of the slurry technique?
time consuming
53
Superficial skin scraping evaluates a __ surface area than deep
wider
54
How should you adjust the microscope before looking at a skin scrape?
10x mag only, lower condenser, close the diaphragm
55
What is a trichogram used to evaluate for?
demodex (less sensitive than scrape but less invasive), dermatophytes, barbering, hair cycle phase